DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and serpina1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_017207927.1	Gene:	serpina1 / 322701	ZFINID:	ZDB-GENE-030131-1421	Length:	433	Species:	Danio rerio

Alignment Length:	380	Identity:	109/380 - (28%)
Similarity:	196/380 - (51%)	Gaps:	31/380 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGL--------QLG 67
            ||.:|...:..:...|.|    |..|||..:..||:|..:||..||..::.:||        |:.
Zfish    73 FAFSLYKKLASNPDGQGK----NIFFSPVGISMALSLLAVGAKASTLSQIYSGLGYSALTPEQVN 133

  Fly    68 PGDRHHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFAD 132
            .|..|.:.:         ..:......|::...:.:.|..:::.:|.:.|..::.|:|....|:.
Zfish   134 EGYEHLLHM---------LGHSQDAMQLEAGAGVAIRDGFKVVDQFLKDAQHYYNSEAFGVDFSK 189

  Fly   133 SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDR 197
            .|.|...||.::.::|..||||:::.  ::.:|..:|||.:||:|||:|||..:.|....|.||:
Zfish   190 PEIAAAEINKFIARKTHDKITNMVKD--LDADTVMMLINYMYFRGKWEKPFDAKLTHKADFKVDQ 252

  Fly   198 DTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADI 262
            ||.|||:||.:..::...:.|..:...:.:||. .|..|:|:||:: ..::|||:.:....|.:.
Zfish   253 DTTVQVDMMKRTGRYDIYQDPVNQTTVMMVPYK-GNTSMMIVLPDD-GKMKELEESICRHHLKNW 315

  Fly   263 DAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYID 327
            ...|....|::|:|:..|.....|..:|..:|:|:.|:|||...|: |.:...|:|...|:..:.
Zfish   316 HDKLFRSSVDLFMPKFSISATSKLDGILKDMGMTDAFNDKADFSGM-TEEVKVKVSQVLHQAVMS 379

  Fly   328 VNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYI--RNPQAVFFAGRFSNP 380
            |:|.|:||||::.::|:||.|.....|   :.||:..|  .:..::.|.|:.:||
Zfish   380 VDEKGTEAAAITTIEIMPMSLPDTVIL---NRPFLVLIVEDSTMSILFMGKITNP 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	107/375 (29%)
serpina1	XP_017207927.1	alpha-1-antitrypsin_like	69..428	CDD:239011	107/375 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010