DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpina1f

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001101524.1	Gene:	Serpina1f / 314406	RGDID:	1307899	Length:	412	Species:	Rattus norvegicus

Alignment Length:	388	Identity:	77/388 - (19%)
Similarity:	168/388 - (43%)	Gaps:	46/388 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLG----PGDRHHI 74
            |:...:.|:..|.|.:.  |.:|||..|.:|:::..:||.|:.::.:...|:|.    |....|.
  Rat    50 NISITLFKEMAQLSVNG--NILFSPIRVIAAISMLSLGAKGNESKRILEILRLNKTGLPEAEIHK 112

  Fly    75 ALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQL 139
            ..   .:...:.:..::...|||.:.::::..|..:.:|.|...:.:.|...:..|.|...|...
  Rat   113 CF---RYLLRAIHQPEQLSPLKSGSGVFIHQDLTPVDKFVEGVKNLYHSDIVSINFTDCRRAKTQ 174

  Fly   140 INDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVN 204
            ||:::..::..:|.|::::  :.|:|...::|.:.:..|....|...:.....:|:::...::|.
  Rat   175 INNYMMTKSNKEIKNIVKN--LENDTYMAVVNYIIWNAKINSDFGCRSVKQKDYHLEQGMTIKVP 237

  Fly   205 MMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQ 269
            |::..|......:..|.:..:......||.....::| ::..:|::||:|.......:.....|:
  Rat   238 MIHIVDLNHLFRVEDLSSTVLVFTLLASNFTTYFIIP-DIGQMQKVEQRLTYPHFRRMRRQSNLR 301

  Fly   270 DVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFT---SQSGQKISAARHRGYIDVNEA 331
            .|.:..|.:.:....|::.::|.||||.||::.|....:..   .:|.:.:|..:    :.:::.
  Rat   302 MVNLETPELSLSETHDVESMMNLLGITYVFNNDANSSAVMNDTLQKSFKMVSKVK----LTIDDK 362

  Fly   332 GSEAAAVSFMKIVPMMLNMNKKLFKAD-----------HPFVFYIRNP--QAVFFAGRFSNPK 381
            ||:..              ....||.|           .||:.:|::|  ....|.||..|||
  Rat   363 GSKPG--------------RSTCFKNDGSVDVGYVQFNRPFLIFIKDPTNDVPLFLGRVVNPK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	73/382 (19%)
Serpina1f	NP_001101524.1	serpin	47..410	CDD:422956	74/385 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100