DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001100821.1	Gene:	Serpinb9d / 306890	RGDID:	1308725	Length:	337	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	105/359 - (29%)
Similarity:	179/359 - (49%)	Gaps:	47/359 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLT 111
            :..:||.|.||.::...|.|.......|..:| :....:.|.......|:..|||:..::.:|:.
  Rat     1 MVLLGAKGDTAVQISQALNLNKHPDEDIHKDF-QLLLHNLNKPKSHYCLRIANRLFAENTCKLVP 64

  Fly   112 EFNEIAVDFFQSKAEATRFAD-SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYF 175
            .:.|..:.|:.|:.|...||. :|.:.:.||.||.::||.||..||.||:|.:||..:::|.|||
  Rat    65 TYKESCLRFYNSEIEQLSFAKAAEESRKHINTWVSKQTEGKIPELLSSDSVGSETKLIMVNALYF 129

  Fly   176 KGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILL 240
            :|.|...|..|.|....|.:::.....|.||:||:.|..|.:.:::|:.:.:||....:..::||
  Rat   130 QGSWLHCFDKEFTMEMPFKINKKETKPVQMMWQEETFDVAYVKEIQAQILVMPYRGMEMSFMVLL 194

  Fly   241 PNEVNGLQELEQQLNTVDLADIDAALTLQ--------------DVEIFLPRMCIEYDVDLKQVLN 291
            |:|            .||:..::::||.:              :|.::||:..::...|:..:..
  Rat   195 PDE------------GVDIRKVESSLTFEKLTAWTKPEFIYSTEVYVYLPKFQLQEQYDMTALFQ 247

  Fly   292 QLGITEVFSD-KAKLDGLFTSQSGQKISAARHRGYIDVNEAGSEAAAV-------SFMKIVPMML 348
            .||:.:|||: ||.|.|: ..:....:|...|...::|||.|:||||.       |..:..|
  Rat   248 HLGMIDVFSEIKADLSGM-CPEKDLCVSKFVHECVVEVNEEGTEAAAASAADCCYSCSEYTP--- 308

  Fly   349 NMNKKLFKADHPFVFYIRNPQ--AVFFAGRFSNP 380
                 .|.||.||:|:||:.|  ::.|.||||:|
  Rat   309 -----TFCADRPFLFFIRHNQTNSILFCGRFSSP 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	101/354 (29%)
Serpinb9d	NP_001100821.1	SERPIN	1..337	CDD:294093	104/357 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_115848
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730