DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinb13

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001100638.1	Gene:	Serpinb13 / 304690	RGDID:	1304661	Length:	389	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	108/374 - (28%)
Similarity:	186/374 - (49%)	Gaps:	36/374 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NTVFSPASVQSALTLAFMGASGSTAEELRNGL--QLGPGD----------------RHHIALNFG 79
            |..|||..:.:|:.:..:|..|:||.||:..|  :.|.|.                .|.......
  Rat    26 NVFFSPLGISTAIGMILLGTQGATASELQKVLYSEQGTGSSRLKSEEKEIEKTEEIHHQFQKLLT 90

  Fly    80 EFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFAD-SEGATQLINDW 143
            |..:.:.:|.     |...||||...:...|.::.:....::.:..|...|.: ::.:.:.||.|
  Rat    91 EISKPTKDYD-----LIISNRLYGERTYLFLQKYIDYVEKYYHASLEPVDFVNAADESRKKINSW 150

  Fly   144 VEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQ 208
            ||.:|..|:.:|....::|:.|..:|||.:||||.|.:.|..|.|..:.|.::::....|.||.|
  Rat   151 VESQTNEKVKDLFPEGSLNSSTKLVLINTVYFKGLWDREFKKEHTKEEDFWLNKNISKPVQMMAQ 215

  Fly   209 EDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLAD--IDAALTLQDV 271
            ...|.|..|..|:|:.|.:||..|:..|.:||||:::||:::..:|:...|.:  ....|..:.|
  Rat   216 CSSFSFTLLEDLQAKIVGIPYKNSDFSMFVLLPNDIDGLEKIIDKLSPEKLVEWTSPGQLKQRKV 280

  Fly   272 EIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYIDVNEAGSEAA 336
            ::.|||:.:|...||:..|..:||...||:.|...|: ::.||.:.....||.::.|.|.|.||.
  Rat   281 DLRLPRLKVEETYDLQPTLEAVGIHSAFSEHADYSGM-SAHSGLQTQNFLHRSFLVVTEEGVEAT 344

  Fly   337 A---VSFMKIVPMMLNMNKKLFKADHPFVFYIRNPQ--AVFFAGRFSNP 380
            |   |.|    .::...:.:|...:|||:|::|:.:  ::.|.||||:|
  Rat   345 AGTGVGF----KVLSAASCELVHCNHPFLFFVRHRESDSILFFGRFSSP 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	104/369 (28%)
Serpinb13	NP_001100638.1	SERPIN	4..389	CDD:294093	107/372 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830