DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinb3

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001382662.1	Gene:	Serpinb3 / 304688	RGDID:	1549766	Length:	387	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	118/383 - (30%)
Similarity:	200/383 - (52%)	Gaps:	29/383 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 TKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLG-----PGDR---HHIAL 76
            |.:..:|.:|...|..:||.|:.:||.:..:||.|:|.:::...|||.     |.::   .|...
  Rat    12 TLELYRQLRDSEDNIFYSPLSIMTALAMLQLGAKGNTEKQIEKALQLSETTKKPKEKSADSHDEE 76

  Fly    77 NFGEFWR---TSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFAD-SEGAT 137
            |..|.:|   ...|..:....|||.|.:|.......|..|.|....::|:..|:..||. :|.:.
  Rat    77 NVHEQFRKIMNQLNKSNGAYDLKSPNSIYGAKGFPFLQTFMEDIKKYYQANVESLDFAHAAEESQ 141

  Fly   138 QLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQ 202
            :.||.|||.:|..||.:|....::|:.|..:|:|.:||||:|...|..:.|..|.|.::::|...
  Rat   142 KKINSWVENKTNGKIKDLFPRGSLNSSTILVLVNAVYFKGQWNHKFDEQRTREDKFWLNKNTSKP 206

  Fly   203 VNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALT 267
            |.||.|.::|.|..|..::|:.|::||....:.|.||||.|::||::||::|:    ||...|.|
  Rat   207 VQMMRQTNEFNFIFLEDVQAKMVEIPYKGKELSMFILLPMEIDGLKKLEEKLS----ADTLLAWT 267

  Fly   268 ------LQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFS-DKAKLDGLFTSQSGQKISAARHRGY 325
                  :..:.:.|||..::...||...|..:|:.:.|: .||...|: :|..|..:|...|:.:
  Rat   268 SPKNMRMTQLNLSLPRFKVQEKYDLPGPLEHMGMVDAFNPQKADFSGM-SSTKGLVVSKVLHKSF 331

  Fly   326 IDVNEAGSEAAAVSFMKIVPMMLNMNKKL-FKADHPFVFYIR--NPQAVFFAGRFSNP 380
            ::|||.|:||||.:  .:...:|:..:.. |..:.||:.:|:  |..::.|.||.|:|
  Rat   332 LEVNEEGAEAAAAT--GVETRILSAPRTTEFTCNRPFIVFIKPNNTNSILFFGRVSSP 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	115/378 (30%)
Serpinb3	NP_001382662.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930