DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and LOC299277

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_008763124.2	Gene:	LOC299277 / 299277	RGDID:	1595900	Length:	420	Species:	Rattus norvegicus

Alignment Length:	371	Identity:	103/371 - (27%)
Similarity:	182/371 - (49%)	Gaps:	36/371 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIAL--NFGEFWRTSCNYGD 90
            |:|:.|..|||.|:.:||....:||.|:|.:|:..||:....:...|.:  |:.:..:.....|.
  Rat    65 KNPNKNIAFSPLSISAALASLSLGAKGNTLQEILEGLKFNLTETTEIDIHQNYRDLLQRLSQPGG 129

  Fly    91 RGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQLINDWVEQETEHKITNL 155
            :|.:.:: |.|:|...|::|..|.|.|...:|::..||.|..:..|.:.|||:|..:::.||..:
  Rat   130 QGQISRA-NLLFVEKHLQILNGFKEKAKALYQTEVFATDFQQTCEARKFINDYVMIQSQGKIKEM 193

  Fly   156 LQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQED---KFRFAEL 217
            :..  :...||.:::|.|.|.|:|..||.|:.|.:..|.:|....|:|.||..||   .:.:.|
  Rat   194 VTE--LEERTSIVMLNFLLFTGQWSVPFDPDDTFMGKFILDSRRPVKVLMMKTEDLTTPYFWDE- 255

  Fly   218 PQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQDV-EIFLPRMCIE 281
             :||...|:|.|......|.| ||:: ..::::|..|:...|.....:|..:.: |:.||:..:.
  Rat   256 -ELKCTVVELNYKGHGKAMFI-LPDQ-GKMEQVEASLHPGTLRKWTDSLKPRIIDELHLPKFSLS 317

  Fly   282 YDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQK---ISAARHRGYIDVNEAGSEAAAVSFMKI 343
            ....|:.:|.:|||.:||:.:|.|.|:    :|.|   :|...|...:.:.|.|:||.|.:
  Rat   318 KTYKLENILPELGIMDVFNTQADLSGI----AGAKDVRVSQMIHNTVLGMAETGTEAEATT---- 374

  Fly   344 VPMMLNMNKKLFKADHPFVFYIR---------NPQAVFFAGRFSNP 380
               .:..|.:..|.:..||.::|         |.:.:.|..:..||
  Rat   375 ---RVEYNFRPAKLNDTFVNFVRKFLYMVLEPNSELISFMRKVINP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	101/366 (28%)
LOC299277	XP_008763124.2	serpinA3_A1AC	37..417	CDD:381019	101/369 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010