DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinf2

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001011892.1	Gene:	Serpinf2 / 287527	RGDID:	1306692	Length:	491	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	99/375 - (26%)
Similarity:	171/375 - (45%)	Gaps:	32/375 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGD-RHHI 74
            |..:|..::.:.:...      |.|.||.||..||:...:||...|.|.|:..|.:..|. ..|:
  Rat    89 FTTDLFSLVAQTSTSS------NLVLSPLSVALALSHLALGARNQTLENLQRVLHMNMGSCIPHL 147

  Fly    75 ALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQL 139
            ..:|       |...:.| .::...|:|:.....:..:|.|.:...|.:|.........|....
  Rat   148 LSHF-------CQNLNPG-TIRLAARIYLQKGFPIKDDFLEQSEKLFGAKPVKLTGRQEEDLMN- 203

  Fly   140 INDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVN 204
            ||.||::.||.||.:.| |:..:| |..||:|.::|.|.|:..|.|..|..|.||:|....|.|.
  Rat   204 INKWVKEATEGKIEDFL-SELPDN-TVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVA 266

  Fly   205 MMY-QEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVN-GLQELEQQLNTVDLADIDAALT 267
            ||: |....|:..|.|.:.:....|:. :|:..::::|.... .:.|:...|....|  ...::.
  Rat   267 MMHAQSYPLRWFLLEQPEIQVAHFPFQ-NNMSFVVIMPTYFGWNVSEVLANLTWDTL--YQPSMR 328

  Fly   268 LQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYIDVNEAG 332
            .:..::.||::.:|..:||...|::||:.::| ....|.|:  |.....:|:.:|:..::::|||
  Rat   329 EKPTKVRLPKLHLEQHLDLVATLSKLGLQDLF-QSPDLRGI--SDQSLVVSSVQHQSTMELSEAG 390

  Fly   333 SEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRNPQ--AVFFAGRFSNP 380
            .||||.:...:..|.|:.    |..:.||:|:|....  ...|.|...||
  Rat   391 VEAAAATSTAMTRMSLSS----FFLNRPFIFFIMEETIGIPLFVGSVRNP 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	97/370 (26%)
Serpinf2	NP_001011892.1	alpha2AP	82..433	CDD:239008	97/370 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010