DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42Dc and Serpina1c

DIOPT Version :9

Sequence 1:NP_001246154.1 Gene:Spn42Dc / 35600 FlyBaseID:FBgn0033113 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_033271.1 Gene:Serpina1c / 20702 MGIID:891969 Length:413 Species:Mus musculus


Alignment Length:382 Identity:118/382 - (30%)
Similarity:197/382 - (51%) Gaps:23/382 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 NQFARNLIDV---ITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQL---- 66
            ::.|.||.|.   :.::.:.||...  |..|||.|:.:|..:..:|:.|.|..::..|||.    
Mouse    42 HEIATNLGDFAISLYRELVHQSNTS--NIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQ 104

  Fly    67 -GPGDRHHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRF 130
             ...|.|.   :|....:| .|..|....|.:.|.|:||:.|:|:.:|.|.|.:.:|::..:..|
Mouse   105 TSEADIHK---SFQHLLQT-LNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNF 165

  Fly   131 ADSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHV 195
            |:||.|.::|||:||:.|:.||...::.  ::.:|...|.|.:.|||||:|||.||.|....|||
Mouse   166 AESEEAKKVINDFVEKGTQGKIAEAVKK--LDQDTVFALANYILFKGKWKKPFDPENTEEAEFHV 228

  Fly   196 DRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLA 260
            |..|.|:|.||.............|.:..:.:.| ..|...:.|||:: ..:|.|||.|:...::
Mouse   229 DESTTVKVPMMTLSGMLDVHHCSTLSSWVLLMDY-AGNATAVFLLPDD-GKMQHLEQTLSKELIS 291

  Fly   261 DIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGY 325
            ........:..:|..||:.|..:.:||.:::.||||.:|::.|.|.|:....:..|:|.|.|:..
Mouse   292 KFLLKRPRRLAQIHFPRLSISGEYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAV 356

  Fly   326 IDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYI--RNPQAVFFAGRFSNP 380
            :.::|.|:||||.:.:..||..:   ..:.:.||||:|.|  .:.|:..|.|:..:|
Mouse   357 LTMDETGTEAAAATVLLAVPYSM---PPIVRFDHPFLFIIFEEHTQSPLFVGKVVDP 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DcNP_001246154.1 SERPIN 7..377 CDD:238101 117/377 (31%)
Serpina1cNP_033271.1 SERPIN 53..410 CDD:214513 113/369 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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