DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinf1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_035470.3	Gene:	Serpinf1 / 20317	MGIID:	108080	Length:	417	Species:	Mus musculus

Alignment Length:	369	Identity:	94/369 - (25%)
Similarity:	165/369 - (44%)	Gaps:	29/369 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNY 88
            |:.|..|..|.:.||.||.:||:...:||...|...:...|.........|...:.|. ..|...
Mouse    67 LRSSASPTGNVLLSPLSVATALSALSLGAEHRTESVIHRALYYDLITNPDIHSTYKEL-LASVTA 130

  Fly    89 GDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQL--INDWVEQETEHK 151
            .::.  |||.:|:.....|.:.:.|   .....:|.....|.........|  ||:||:.:.:.|
Mouse   131 PEKN--LKSASRIVFERKLRVKSSF---VAPLEKSYGTRPRILTGNPRVDLQEINNWVQAQMKGK 190

  Fly   152 ITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDK--FRF 214
            |..  .:..:.:..|.||:.|.||||:|...|....|::..||:|.|..|:|.|| .:.|  .|:
Mouse   191 IAR--STREMPSALSILLLGVAYFKGQWVTKFDSRKTTLQDFHLDEDRTVRVPMM-SDPKAILRY 252

  Fly   215 AELPQLKARAVQLPYDYSNIHMLILLPNEV-NGLQELEQQLNTVDLADIDAAL-TLQDVEIFLPR 277
            .....|..:..|||.. .::.::..||..| ..|..:|:.|.:..:.|||..| |:|.| :.:|:
Mouse   253 GLDSDLNCKIAQLPLT-GSMSIIFFLPLTVTQNLTMIEESLTSEFIHDIDRELKTIQAV-LTVPK 315

  Fly   278 MCIEYDVDLKQVLNQLGITEVFS--DKAKLDGLFTSQSGQKISAARHRGYIDVNEAGSEAAAVSF 340
            :.:.::.:|.:.|..:.:..:|.  |.:|:.|     ...|::...||...:.||.|:.::....
Mouse   316 LKLSFEGELTKSLQDMKLQSLFESPDFSKITG-----KPVKLTQVEHRAAFEWNEEGAGSSPSPG 375

  Fly   341 MKIVPMMLNMNKKLFKADHPFVFYIRNPQ--AVFFAGRFSNPKS 382
            ::.|.:...::   :..:.||:|.:|:..  |:.|.||..:|.|
Mouse   376 LQPVRLTFPLD---YHLNQPFLFVLRDTDTGALLFIGRILDPSS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	91/362 (25%)
Serpinf1	NP_035470.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	17..41
Serpinf1	NP_035470.3	PEDF	39..414	CDD:239007	92/365 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010