DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpini2

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001127881.1	Gene:	Serpini2 / 171149	RGDID:	619897	Length:	405	Species:	Rattus norvegicus

Alignment Length:	412	Identity:	109/412 - (26%)
Similarity:	196/412 - (47%)	Gaps:	46/412 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEPQEGRNQFARN---LIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRN 62
            :|..|..|....:|   .:|:....:|....    |.:|||......|.:..:||.|...:::..
  Rat    13 LSGSQTSRTMDQKNAEFAVDLYKAISLSNKN----NVIFSPLGTTVLLGMVQLGAKGKAQQQIMQ 73

  Fly    63 GLQLGPGDRHHIALNFGEFWRTSCNYGDRGPVLKSV----------------NRLYVNDSLELLT 111
            .|::               .:||.  |:...||||:                :.||:.:...:..
  Rat    74 TLRM---------------QKTST--GEEFSVLKSLFSAISKKKQEFTFNLASALYLQEGFIVKE 121

  Fly   112 EFNEIAVDFFQSKAEATRFADSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFK 176
            .:.....:||||..:...|.|::.:.|.|:.|||.:|:.||.|:...:.....|..:|:|.:|||
  Rat   122 SYLHSNKEFFQSATKLVDFLDAKTSAQAISTWVESKTDGKIKNMFSEEDFGPLTRLVLVNAIYFK 186

  Fly   177 GKWQKPFMPETTSIDHFHVDRDTHVQVNMM--YQEDKFRFAELPQLKARAVQLPYDYSNIHMLIL 239
            |.|::.|..|.|.:..|.....:.|::.||  ....|:.:.....:..:.::|||......::||
  Rat   187 GDWKQKFRKEDTEMTDFSKKDGSTVKIPMMKALLRAKYGYFSESSMTYQVLELPYKADEFSLVIL 251

  Fly   240 LPNEVNGLQELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAK 304
            ||.|...::|:|:|:....:....:.|..::||:.|||..||..:|.|:.|..|.:||:||....
  Rat   252 LPTEDVNIEEVEKQVTARHVQKWFSELHEEEVEVSLPRFKIEQKLDFKEALFSLNVTEIFSGGCD 316

  Fly   305 LDGLFTSQSGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRNPQ 369
            |.|: |..|...:|.|..:.:.::||.||||||.:.:.| |.::::.:..|.|:|||:|.:::.|
  Rat   317 LSGI-TDSSELYVSRAMQKVFFEINEDGSEAAASTGINI-PAIMSLTQTQFLANHPFLFIMKHIQ 379

  Fly   370 --AVFFAGRFSNPKSGSGSGEE 389
              ::.|.|:.::|...:..|.:
  Rat   380 TESILFMGKVTDPDIHTVKGRD 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	105/392 (27%)
Serpini2	NP_001127881.1	SERPIN	23..405	CDD:294093	106/402 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.030