DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42Dc and Serpind1

DIOPT Version :9

Sequence 1:NP_001246154.1 Gene:Spn42Dc / 35600 FlyBaseID:FBgn0033113 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_001317976.1 Gene:Serpind1 / 15160 MGIID:96051 Length:478 Species:Mus musculus


Alignment Length:398 Identity:109/398 - (27%)
Similarity:185/398 - (46%) Gaps:60/398 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 QFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHI 74
            :||.||..|: ||....|.    |...:|..:.:|:.:..:|..|.|.||:            |.
Mouse   111 KFAFNLYRVL-KDQATTSD----NLFIAPVGISTAMGMISLGLRGETHEEV------------HS 158

  Fly    75 ALNFGEFWRTSCNY------------------GDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFF 121
            .|:|.:|...|..|                  .:.|..|:|||.||:.....:..:|.....:|:
Mouse   159 VLHFRDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLRSVNGLYIQKQFPIREDFKAAMREFY 223

  Fly   122 QSKAEATRFADSEGATQLINDWVEQETEH--KITNLLQSDAVNN---ETSALLINVLYFKGKWQK 181
            .::|:...|.|..        ::.:...|  |:|..|..:|:.|   .|..|::|.:||||.|..
Mouse   224 FAEAQEANFPDPA--------FISKANNHILKLTKGLIKEALENIDPATQMLILNCIYFKGTWVN 280

  Fly   182 PFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNG 246
            .|..|.|...:|.::....|:|:||..:..|..|...:|....:||.| ...|.|||::|.:::|
Mouse   281 KFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEY-VGGISMLIVVPRKLSG 344

  Fly   247 LQELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTS 311
            ::.||.||....:.....::|.:..|:.||:..:|.:.:|.:||..:|||::|:....:.|:   
Mouse   345 MKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGI--- 406

  Fly   312 QSGQKIS--AARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVF--YIRNPQAVF 372
             |.|:|:  ..:|:..|.|||.|::||||:.:..:|:...:.   |..|.||:|  |......:.
Mouse   407 -SDQRIAIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVR---FTVDRPFLFLVYEHRTSCLL 467

  Fly   373 FAGRFSNP 380
            |.|:.:||
Mouse   468 FMGKVTNP 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DcNP_001246154.1 SERPIN 7..377 CDD:238101 107/393 (27%)
Serpind1NP_001317976.1 HCII 43..476 CDD:239002 109/398 (27%)
2 X 11 AA approximate repeats, Asp/Glu-rich (acidic) (hirudin-like) 54..78
Glycosaminoglycan-binding site. /evidence=ECO:0000250 171..191 1/19 (5%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.020

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