DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinc1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_543120.1	Gene:	Serpinc1 / 11905	MGIID:	88095	Length:	465	Species:	Mus musculus

Alignment Length:	391	Identity:	112/391 - (28%)
Similarity:	197/391 - (50%)	Gaps:	24/391 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EPQEGRNQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLG 67
            |..:..::||.|..     ..|..||:.:.|...||.|:.:|..:..:||...|.::|....:..
Mouse    83 ELSKANSRFATNFY-----QHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFD 142

  Fly    68 -----PGDRHHIALNFGEFWRTSCNY---GDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSK 124
                 ..|:.|..     |.:.:|..   .::...|.|.|||:.:.||.....:.:::...:.:|
Mouse   143 TISEKTSDQIHFF-----FAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAK 202

  Fly   125 AEATRFADS-EGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETT 188
            .:...|.:: |.:...||:||..:||.:|.:::...|:|..|:.:|:|.:||||.|:..|.||.|
Mouse   203 LQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENT 267

  Fly   189 SIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQ 253
            ..:.|:........|.|||||.||::..:.: ..:.::||:...:|.|:::||.....|.::||:
Mouse   268 RKEPFYKVDGQSCPVPMMYQEGKFKYRRVAE-GTQVLELPFKGDDITMVLILPKPEKSLAKVEQE 331

  Fly   254 LNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFS-DKAKLDGLFT-SQSGQK 316
            |....|.:....|:...:.:.:||...|....||:.|..:|:.::|| :|::|.|:.. .:....
Mouse   332 LTPELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLY 396

  Fly   317 ISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRNP--QAVFFAGRFSN 379
            :|.|.|:.:::|||.||||||.:.:.|....||.|:..|||:.||:..||..  ..:.|.||.:|
Mouse   397 VSDAFHKAFLEVNEEGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGRVAN 461

  Fly   380 P 380
            |
Mouse   462 P 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	108/382 (28%)
Serpinc1	NP_543120.1	serpinC1_AT3	71..464	CDD:381002	112/391 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030