Protein Alignment Spn42Db and SERPINF2

DIOPT Version :10

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 103/389 - (26%)
• Similarity: 181/389 - (46%)
• Gaps: 64/389 - (16%)

  Fly     7 AQGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQ 71
            |:.:..|...|...:.:.|...|:|.||||:.::.:.|.:|..  :.|.:.:.:.|..|.
Human    99 ARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQ--NHTLQRLQQVLHAGS----- 156

  Fly    72 VAESFGVVLKSY--EQCQVL-----KMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQA 129
                 |..|...  ..||.|     ::|..:|:.||..:.|.|....||.|.:||:.:....|..
Human   157 -----GPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDD 216

  Fly   130 ASIINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTR 194
            .:.||:||:..|...|::.:..  |.:|:.|.|:|.|||:|.|...|:...|:.:.|
Human   217 LANINQWVKEATEGKIQEFLSG--LPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSF-------- 271

  Fly   195 VRMMHVCENFFFAVLPMFEATALRMNYSAC--------------NLAMIILLPDE-KSNLTSLEK 244
                |:.|.|...| .|.:|....:.:...              |::.::|:|.. :.|::.:
Human   272 ----HLDEQFTVPV-EMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSQV-- 329

  Fly   245 KLSDISLEVVSSAMNLEK-VDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLF 308
             |:::|.:.:...:..|: ..|::|....:.|.:|...|..:|:..:|.. .:|.|:  ||:||.
Human   330 -LANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQA-PDLRGI--SEQSLV 390

  Fly   309 VSQIVHKAFIEINEVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDNTHGL-LFAG 371
            ||.:.|::.:|::|||.||||||:...:..|:.:       |..||||.:.|.::|.|| ||.|
Human   391 VSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSS-------FSVNRPFLFFIFEDTTGLPLFVG 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	102/387 (26%)
SERPINF2	XP_005256758.2	serpinF2_A2AP	91..454	CDD:381009	103/389 (26%)