Protein Alignment Spn42Db and SERPINI1

DIOPT Version :9

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 118/391 - (30%)
• Similarity: 208/391 - (53%)
• Gaps: 24/391 - (6%)

  Fly     8 QGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGL---EA 69
            :.:...::.:::.|.......||::|||||.::..|:.:| ::|| |.||:...:.:..|   |.
Human    24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELG-AQGS-TQKEIRHSMGYDSLKNGEE 86

  Fly    70 QQVAESFGVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQA-ASII 133
            ....:.|..::.:.|...|:|:||.|:|..|..|:|:|..::::.|.:....:||....| |:.|
Human    87 FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYI 151

  Fly   134 NKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDR-PTRVRM 197
            |||||:.||||:||::.||.....:.|.|:|.::|||.|...|..:.||...|...|. ..::.|
Human   152 NKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPM 216

  Fly   198 MHVCENFFFAVLPMFEATA------LRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSS 256
            |:....|::.........|      |.:.|....::|:::|..::..|.:||..:....:|..::
Human   217 MYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWAN 281

  Fly   257 AMNLEKVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEIN 321
            ::..:||:|.:|.||.|.:.:|..||..:|:..||...|.|.|:..::| :|:|:.:||:|:|:|
Human   282 SVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKE-IFLSKAIHKSFLEVN 345

  Fly   322 EVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDNTHG-LLFAGHFITTKVEQSEKCN 385
            |.|:||||.:..:|..|.....   |:|. .:.|||:.|::...| :||.|     :|...|..|
Human   346 EEGSEAAAVSGMIAISRMAVLY---PQVI-VDHPFFFLIRNRRTGTILFMG-----RVMHPETMN 401

  Fly   386 T 386
            |
Human   402 T 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	114/372 (31%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	118/391 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	227	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3439
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.980