Protein Alignment Spn42Db and SERPINB10

DIOPT Version :9

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_005015.1
• Gene: SERPINB10 / 5273
• HGNCID: 8942
• Length: 397
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 120/399 - (30%)
• Similarity: 201/399 - (50%)
• Gaps: 39/399 - (9%)

  Fly     4 EEFAQGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEM--------DE 60
            :..|..:.||||.|...|..::.|.||.:|..||..|..::.:|..  ..||.:|        |:
Human     2 DSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAK--GTTAAQMAQVLQFNRDQ 64

  Fly    61 GLR------------FGGLEAQQVAESF----GVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGH 109
            |::            |....::::...|    ..:||..:. .:||.||.:|..|......::..
Human    65 GVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDD-YLLKTANAIYGEKTYAFHNKYLE 128

  Fly   110 ILEQKFRSKPMEIDF--GSEQAASIINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEW 172
            .::..|.::|..::|  .|:|....||.|||.||...|::::....:...:|:.|||.::|||.|
Human   129 DMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIW 193

  Fly   173 SISFNEKETREEDFFGSDRPTR-VRMMHVCENFFFAVLPMFEATALRMNYSACNLAMIILLPDEK 236
            ...|..:.|.|:.|..::..:: |:||.:.:......:...:|..|::.|.:.:|:::||||::.
Human   194 EHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDI 258

  Fly   237 SNLTSLEKKLSDISLEVVSSA--MNLEKVDVKIPSFTAEFQQELSQVLMLMGMNRIFS-GQAELG 298
            :.|..|||.::...|...:||  |.|.:|.:.:|.|..|...:|...|..|||:..|| .:|:..
Human   259 NGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFS 323

  Fly   299 GMLQSEESLFVSQIVHKAFIEINEVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDN 363
            || .|..:||:|.:.||||:||||.||||||.:.:....|.    :.|...|:||.||.:.|:.|
Human   324 GM-SSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRI----RVPSIEFNANHPFLFFIRHN 383

  Fly   364 -THGLLFAG 371
             |:.:||.|
Human   384 KTNTILFYG 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	119/391 (30%)
SERPINB10	NP_005015.1	PAI-2	4..397	CDD:239013	120/397 (30%)
		Nuclear localization signal	74..77		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.930