Protein Alignment Spn42Db and SERPINE2

DIOPT Version :10

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 107/367 - (29%)
• Similarity: 185/367 - (50%)
• Gaps: 47/367 - (12%)

  Fly    29 NIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAESFGVVLKSYEQCQVLKMAN 93
            ||:.||..|.....||::|..  ..|.|::...:|:|.....::.:.....:.|.:...::.:||
Human    62 NIVISPHGIASVLGMLQLGAD--GRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVAN 124

  Fly    94 GLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAASI---INKWVESQTNNLIKDIIGP---- 151
            .::|....:::..|....:..|:.:...::|  |..||.   ||.||:::|.::|.:::.|
Human   125 AVFVKNASEIEVPFVTRNKDVFQCEVRNVNF--EDPASACDSINAWVKNETRDMIDNLLSPDLID 187

  Fly   152 RVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSD-RPTRVRMMHVCENFFFAVLPMFEAT 215
            .|||   ||.|||.::|||.|...|..:.|::..|..:| :..:|.|:        |.|.:|...
Human   188 GVLT---RLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPML--------AQLSVFRCG 241

  Fly   216 A-----------LRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNL---EKVDVK 266
            :           :.:.|...:::|:|.||.|.|  |.|...:..||.:.:.|.|::   ::|.|.
Human   242 STSAPNDLWYNFIELPYHGESISMLIALPTESS--TPLSAIIPHISTKTIDSWMSIMVPKRVQVI 304

  Fly   267 IPSFTAEFQQELSQVLMLMGMNRIF-SGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAAA 330
            :|.|||..|.:|.:.|.::|:..:| |.:|....:....|:|.||.|:.||.||::|.||:|:||
Human   305 LPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAA 369

  Fly   331 TAAVATFRSMPARQGPPKVFHANRPFFYAIKDN-THGLLFAG 371
            |.|:     :.||..|| .|..:|||.:.|:.| |..:||.|
Human   370 TTAI-----LIARSSPP-WFIVDRPFLFFIRHNPTGAVLFMG 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	107/367 (29%)
SERPINE2	XP_005246698.1	serpinE2_GDN	33..408	CDD:381039	107/367 (29%)