Protein Alignment Spn42Db and SERPINA4

DIOPT Version :10

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 105/383 - (27%)
• Similarity: 179/383 - (46%)
• Gaps: 39/383 - (10%)

  Fly    13 FALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFG--GLEAQQVAES 75
            ||...:..:...:.|.||.:|||||..:.|||.:|..  |.:..::.|||.|.  .|....|...
Human    95 FAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGAC--SHSRSQILEGLGFNLTELSESDVHRG 157

  Fly    76 FGVVLKSYE---QCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDF----GSEQAASII 133
            |..:|.:..   .....::.:.|::...|:...:|.:.....:.:|....:|    |:.|   :|
Human   158 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ---LI 219

  Fly   134 NKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTRVR-- 196
            |..|:.:|...|.|::..  |.||..:.|||.|:||..|...|....|..:||: .|..|.||
Human   220 NDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFY-VDENTTVRVP 281

  Fly   197 -MMHVCENFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNL 260
             |:...|:.::........:.|||:|.. :..:..:||:: ..:..:|:.|:.   |::....||
Human   282 MMLQDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILPNQ-GKMREIEEVLTP---EMLMRWNNL 341

  Fly   261 -------EKVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFI 318
                   :|:::.:|.|:......|.|:|..:|...:||..|:|.| :..::.|..|:..|||.:
Human   342 LRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG-ITKQQKLEASKSFHKATL 405

  Fly   319 EINEVGTEAAAATA-AVATFRSMPARQGPPKVFHANRPFFYAI-KDNTHGLLFAGHFI 374
            :::|.||||||||: |:..|.:...|.    :...||||...| ..:|..:||.|..:
Human   406 DVDEAGTEAAAATSFAIKFFSAQTNRH----ILRFNRPFLVVIFSTSTQSVLFLGKVV 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	104/379 (27%)
SERPINA4	NP_001275961.1	serpinA4_KST	81..463	CDD:381020	105/383 (27%)