DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Spn28F

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	125/370 - (33%)
Similarity:	205/370 - (55%)	Gaps:	21/370 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAESF 76
            :||...:..|.:.:|..|:|.||||:.|:.:|..||..  :.||:||...|:... :.::||..:
  Fly    16 RFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGAR--AKTAQEMRNVLKLPD-DKKEVAAKY 77

  Fly    77 GVV---LKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDF-GSEQAASIINKWV 137
            ..:   |:..|:...|.:||.:||.|..|:...:..:::..|.::...||. ...:|:||:|.||
  Fly    78 KDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNWV 142

  Fly   138 ESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSD-RPTRVRMMHVC 201
            ::||...|||::....::| ..|.::|.|:|||:|...||.|.|::.:|..|| :...|.||.:.
  Fly   143 DNQTRGKIKDLVSSNDMSK-MELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLF 206

  Fly   202 ENFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNLEKVDV- 265
            ::|..|......|..:.:.|...:|:|:|.|||:...|:.||||       :|.....|.|:||
  Fly   207 QSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKK-------IVGFKPKLSKMDVT 264

  Fly   266 -KIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAA 329
             ::|.|..||..:|::||:.||:...|...|:...:::: .::.|.:::||||||:||.|.||||
  Fly   265 LRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVEN-SNVHVKKVIHKAFIEVNEEGAEAAA 328

  Fly   330 ATAAVATFRSMPARQGPPKVFHANRPFFYAIKDNTHGLLFAGHFI 374
            |||.:....||| ......||:|:.||.|.|:|. ..:.|.|||:
  Fly   329 ATALLFVRYSMP-MPSSQMVFNADHPFAYVIRDR-ETIYFQGHFV 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	123/367 (34%)
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	123/367 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446355
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	9	9.000