DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and serpinb1l4

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_956235.2	Gene:	serpinb1l4 / 335229	ZFINID:	ZDB-GENE-030131-7169	Length:	433	Species:	Danio rerio

Alignment Length:	438	Identity:	132/438 - (30%)
Similarity:	212/438 - (48%)	Gaps:	77/438 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EEFAQGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFG--- 65
            |..:....||:|.|...:...:|..|:.|||:||..:.||:.:| ::|: ||.:|.:.|.|.
Zfish     2 ESLSAANTQFSLNLFKKISGGNASGNVFYSPVSISSALAMVSLG-AKGN-TADQMFKVLGFNNPP 64

  Fly    66 --------------------GLEAQ---------------------------------QVAESFG 77
                                |:::|                                 |:..||.
Zfish    65 KPGGATPTPAQATQKPKWTCGVKSQHEPQALQQPQKFELPADLKKCPAQPVPGQKAEEQIHSSFN 129

  Fly    78 VVLKSYEQ---CQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAASI--INKWV 137
            .::....:   ..||.:||.||..:..|..|::....::.:.:...::||.::..||.  |||||
Zfish   130 KLMSELNKPGAPYVLSLANRLYGEQTYQFLEKYLSDAKKYYAAGLEKVDFKNKSEASCVNINKWV 194

  Fly   138 ESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTR-VRMMHVC 201
            |..|...|||::....:...:||.|||.|:|||.|...|.::.|::..|..:...|: |:|||..
Zfish   195 EKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEKKFPKEATKDGQFKLNKNQTKPVKMMHQK 259

  Fly   202 ENFFFAVLPMFEATALRMNYSACNLAMIILLPDE----KSNLTSLEKKLSDISLEVVSSAMNLEK 262
            ..|.|.|:|...:..|.:.|...||:|:|:||||    .:.|..||:.|:...|...:..|..::
Zfish   260 AQFPFVVIPEINSQILELPYVGKNLSMLIILPDEIEDATTGLQKLERALTYEKLMQWTKVMRQQE 324

  Fly   263 VDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQ-AELGGMLQSEESLFVSQIVHKAFIEINEVGTE 326
            |.|.:|.|..|...::..:|:.|||..:|..| ..|.|| .|...|.:|:::||||:|:||.|||
Zfish   325 VQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGM-SSSNDLVLSKVIHKAFVEVNEEGTE 388

  Fly   327 AAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDN-THGLLFAGHF 373
            |||||.||.:.|::      .::|:|:.||.:.|:.| |:.:||.|.|
Zfish   389 AAAATGAVVSIRTL------AQIFNADHPFLFFIRHNSTNTILFYGRF 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	130/428 (30%)
serpinb1l4	NP_956235.2	SERPIN	4..433	CDD:294093	131/436 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2586
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.830