DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Serpina7

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_808588.3	Gene:	Serpina7 / 331535	MGIID:	3041197	Length:	426	Species:	Mus musculus

Alignment Length:	373	Identity:	107/373 - (28%)
Similarity:	178/373 - (47%)	Gaps:	22/373 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFG-----GLEAQQV 72
            ||..|:..|...:..|||.:||:||.::.|||..|:  ||:|..::.|.|.|.     ..|.||.
Mouse    60 FAFSLYRRLSVENPDLNIFFSPVSISVALAMLSFGS--GSSTQTQILEVLGFNLTDTPVTELQQG 122

  Fly    73 AESFGVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAAS-IINKW 136
            .:.....|...:....|:|.|.:::.:.|:...:|...::..:.::....||.:..||. .||.:
Mouse   123 FQHLICSLNFPKNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHKINSY 187

  Fly   137 VESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTRVR--MMH 199
            ||.||...|..:|  :.|..:..:.|||.|||:.:|:..|...:|.|...|..|:.|.|:  |||
Mouse   188 VEKQTKGKIVGLI--QGLKLNIIMILVNYIHFRAQWANPFRVSKTEESSNFSVDKSTTVQVPMMH 250

  Fly   200 VCENFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNLEKVD 264
            ..|.::..|......|.|:|:||...||:.: ||.| .::..:|..:|..:|:..:..:....|:
Mouse   251 QLEQYYHYVDMELNCTVLQMDYSENALALFV-LPKE-GHMEWVEAAMSSKTLKKWNYLLQKGWVE 313

  Fly   265 VKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAA 329
            :.:|.|:.....:|...|..|||...|:..|:..|:.: :..|.:|...|||.:.|.|.||:..|
Mouse   314 LFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITE-DSGLKLSYAFHKAVLHIGEEGTKEGA 377

  Fly   330 ATAAVATFRSMPARQGPP--KVFHANRPFFYAI-KDNTHGLLFAGHFI 374
            :...    .|:..::.||  .|...:|.|...| :..|..:||.|..:
Mouse   378 SPEV----GSLDQQEVPPLHPVIRLDRAFLLMILEKRTRSVLFLGKLV 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	107/370 (29%)
Serpina7	NP_808588.3	alpha-1-antitrypsin_like	57..419	CDD:239011	106/369 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100