Protein Alignment Spn42Db and SERPINA9

DIOPT Version :10

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_783866.3
• Gene: SERPINA9 / 327657
• HGNCID: 15995
• Length: 417
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 120/386 - (31%)
• Similarity: 175/386 - (45%)
• Gaps: 35/386 - (9%)

  Fly    13 FALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEA-------- 69
            ||..|:..|...:...||.:||:|:..|.|||.:|..  |.|..::.:||.|.....
Human    51 FAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAH--SVTKTQILQGLGFNLTHTPESAIHQG 113

  Fly    70 -QQVAESFGVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAASI- 132
             |.:..|..|..|..    .|||.:.|:|.|.||:...|...:::.:.::....||.:...|..
Human   114 FQHLVHSLTVPSKDL----TLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQAR 174

  Fly   133 INKWVESQTNNLIKDII-GPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFF--GSDRPTR 194
            ||..|:.:|...:.||| |..:||   .:.|||.|.||.:|...|:.:.||:...|  |......
Human   175 INSHVKKKTQGKVVDIIQGLDLLT---AMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 236

  Fly   195 VRMMHVCENFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMN 259
            |.|||..|.|.|.|........|:|:|....:|..:|  ..|..:..||:.||..:|...|.::.
Human   237 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL--PSKGKMRQLEQALSARTLRKWSHSLQ 299

  Fly   260 LEKVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVG 324
            ...::|.||.|:......|..:|..||:..:|...|:..| :...:||.||:..|||.::::|.|
Human   300 KRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSG-IAKRDSLQVSKATHKAVLDVSEEG 363

  Fly   325 TEAAAATAAVATFRSMPARQGPPK-VFHANRPFFYAIKDN-THGLLFAGHFITTKVEQSEK 383
            |||.|||......||   :.||.. ....||.|...|.:. |.|:||.|     |||...|
Human   364 TEATAATTTKFIVRS---KDGPSYFTVSFNRTFLMMITNKATDGILFLG-----KVENPTK 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	115/373 (31%)
SERPINA9	NP_783866.3	serpinA9_centerin	30..417	CDD:381024	120/386 (31%)