DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Serpinb3

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001382662.1	Gene:	Serpinb3 / 304688	RGDID:	1549766	Length:	387	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	132/394 - (33%)
Similarity:	206/394 - (52%)	Gaps:	43/394 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FAQGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFG----- 65
            ||:...||.|.|:..| |.|.. ||.||||||..:.|||::| ::|: |.|::::.|:..
  Rat     4 FAKATTQFTLELYRQL-RDSED-NIFYSPLSIMTALAMLQLG-AKGN-TEKQIEKALQLSETTKK 64

  Fly    66 -------GLEAQQVAESFGVVLK-------SYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFR 116
                   ..:.:.|.|.|..::.       :|:    ||..|.:|..||....:.|...:::.::
  Rat    65 PKEKSADSHDEENVHEQFRKIMNQLNKSNGAYD----LKSPNSIYGAKGFPFLQTFMEDIKKYYQ 125

  Fly   117 SKPMEIDF--GSEQAASIINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEK 179
            :....:||  .:|::...||.|||::||..|||:.....|...:.|.|||.::|||:|:..|:|:
  Rat   126 ANVESLDFAHAAEESQKKINSWVENKTNGKIKDLFPRGSLNSSTILVLVNAVYFKGQWNHKFDEQ 190

  Fly   180 ETREEDFF---GSDRPTRVRMMHVCENFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTS 241
            .|||:.|:   .:.:|  |:||.....|.|..|...:|..:.:.|....|:|.||||.|...|..
  Rat   191 RTREDKFWLNKNTSKP--VQMMRQTNEFNFIFLEDVQAKMVEIPYKGKELSMFILLPMEIDGLKK 253

  Fly   242 LEKKLSDISLEVVSSAMNLE--KVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQ-AELGGMLQS 303
            ||:|||..:|...:|..|:.  ::::.:|.|..:.:.:|...|..|||...|:.| |:..|| .|
  Rat   254 LEEKLSADTLLAWTSPKNMRMTQLNLSLPRFKVQEKYDLPGPLEHMGMVDAFNPQKADFSGM-SS 317

  Fly   304 EESLFVSQIVHKAFIEINEVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIK-DNTHGL 367
            .:.|.||:::||:|:|:||.|.||||||.......|.|.    ...|..||||...|| :||:.:
  Rat   318 TKGLVVSKVLHKSFLEVNEEGAEAAAATGVETRILSAPR----TTEFTCNRPFIVFIKPNNTNSI 378

  Fly   368 LFAG 371
            ||.|
  Rat   379 LFFG 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	130/388 (34%)
Serpinb3	NP_001382662.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930