DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Serpina9

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001100224.1	Gene:	Serpina9 / 299274	RGDID:	1304789	Length:	417	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	121/384 - (31%)
Similarity:	183/384 - (47%)	Gaps:	30/384 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAE-- 74
            :||..|:..|.:.|.|.||::||:||..|.|||.:|..  |||..::   ||..|.....:||
  Rat    51 KFAFLLYQRLAQKSPGQNILFSPVSISTSLAMLSLGAC--SATKTQI---LRSLGFNITHIAEHT 110

  Fly    75 ---SFGVVLKSYEQCQ---VLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAASI- 132
               .|..::.|..:|.   .|:|.:.|::.|.||:..:|...:::.:.:|....||.:...|..
  Rat   111 IHLGFEQLVHSLNECHKDLELRMGSVLFIRKELQLQVKFLDRVKKLYGTKVFSEDFSNAVTAQAQ 175

  Fly   133 INKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTRVR- 196
            ||.:||.:|...:.|:|  :.|...:.:.|||.|.||..|:..|:...|.:...|...:.|.|.
  Rat   176 INSYVERETKGKVVDVI--QDLDSQTAMVLVNHIFFKANWTQPFSAANTNKSFPFLLSKGTTVHV 238

  Fly   197 -MMHVCENFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNL 260
             |||..|:|.|.|......:.|:|:|....:|..:|  ..|..:..||:.||...|...|.::..
  Rat   239 PMMHQTESFAFGVDRELGCSILQMDYRGDAVAFFVL--PGKGKMRQLERSLSPRRLRRWSRSLQK 301

  Fly   261 EKVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVGT 325
            ..:.|.||.|:......|..:|..||:...|:..|:..|:.:: ..|.||:..|||.::::|.||
  Rat   302 RWIKVFIPKFSISASYNLETILPEMGIRDAFNSNADFSGITKT-HFLQVSKAAHKAVLDVSEEGT 365

  Fly   326 EAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKD-NTHGLLFAGHFITTKVEQSEK 383
            ||||||......||   |..|......|.||...:.| ||..:||.|     |||...|
  Rat   366 EAAAATTTKLIVRS---RDTPSSTIAFNEPFLILLLDKNTESILFLG-----KVENPRK 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	117/372 (31%)
Serpina9	NP_001100224.1	serpin	32..417	CDD:422956	121/384 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.110