DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Serpinf1

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_808788.1	Gene:	Serpinf1 / 287526	RGDID:	631369	Length:	418	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	82/363 - (22%)
Similarity:	157/363 - (43%)	Gaps:	43/363 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAESFGVVLKSYEQCQV-LKMA 92
            ||:.||||:..:.:.|.:|..:  .|...:...|.:..:....:..::..:|.|....:. .|.|
  Rat    77 NILLSPLSVATALSALSLGAEQ--RTESVIHRALYYDLINNPDIHSTYKELLASVTAPEKNFKSA 139

  Fly    93 NGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAASIINKWVESQTNNLIKDIIGPRVLTKD 157
            :.:...:.|:|...|...||:.:.::|..:..........||.||::|....|..  ..|.:...
  Rat   140 SRIVFERKLRVKSSFVAPLEKSYGTRPRILTGNPRIDLQEINNWVQAQMKGKIAR--STREMPSA 202

  Fly   158 SRLCLVNGIHFKGEWSISFNEKETREEDF-FGSDRPTRVRMMHVCE-----------NFFFAVLP 210
            ..:.|:...:|||:|:..|:.::|..:|| ...||..||.||...:           |...|.||
  Rat   203 LSILLLGVAYFKGQWATKFDSRKTTLQDFHLDEDRTVRVPMMSDPKAILRYGLDSDLNCKIAQLP 267

  Fly   211 MFEATALRMNYSACNLAMIILLP-DEKSNLTSLEKKLSDISLEVVSSAMNLEKVDVKIPSFTAEF 274
            :           ..::::|..|| ....|||.:|:.|:...:..:...:...:..:.:|.....:
  Rat   268 L-----------TGSMSIIFFLPLTVTQNLTMIEESLTSEFVHDIDRELKTIQAVLTVPKLKLSY 321

  Fly   275 QQELSQVLMLMGMNRIFSGQ--AELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAAATAAVATF 337
            :.:::..|..|.:..:|...  :::.|     :.:.::|:.|:|..|.||.|    |.|::....
  Rat   322 EGDVTNSLQDMKLQSLFESPDFSKITG-----KPVKLTQVEHRAAFEWNEEG----AGTSSNPDL 377

  Fly   338 RSMPARQGPPKVFHANRPFFYAIKD-NTHGLLFAGHFI 374
            :  |.|...|..:|.||||.:.::| :|..|||.|..:
  Rat   378 Q--PVRLTFPLDYHLNRPFIFVLRDTDTGALLFIGRIL 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	82/360 (23%)
Serpinf1	NP_808788.1	PEDF	40..415	CDD:239007	82/363 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010