Protein Alignment Spn42Db and Serpine1

DIOPT Version :10

• Sequence 1: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_036752.2
• Gene: Serpine1 / 24617
• RGDID: 3249
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 396
• Identity: 105/396 - (26%)
• Similarity: 186/396 - (46%)
• Gaps: 43/396 - (10%)

  Fly     1 MKDEEFAQGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFG 65
            :.:...||....|.:.:..|:.:||...|:::||..:....|||::.|:  ..|.:::.:.:.|.
  Rat    26 LPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTA--GKTRQQIQDAMGFN 88

  Fly    66 GLE---AQQVAESFGVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGS- 126
            ..|   |..:.:....::.|:.:.:: ..|:.::|.:.|::.:.|.....:.||:...::||..
  Rat    89 ISERGTAPALRKLSKELMGSWNKNEI-STADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEM 152

  Fly   127 EQAASIINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDR 191
            |:|..|||.|||..|..:|.|::....:.:.:||.|||.::|.|:|...|.|..|.:..|..||.
  Rat   153 ERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDG 217

  Fly   192 PTRVRMMHVCENFF----FAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLE 252
            .|....|....|.|    |......|...|.:.|....|:|.|..|.||           |:.|.
  Rat   218 STISVPMMAQNNKFNYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEK-----------DVPLS 271

  Fly   253 VVSSAMNLEKVD------------VKIPSFTAEFQQELSQVLMLMGMNRIFSG-QAELGGMLQSE 304
            .:::.::.|.:.            :.:|.|:.|.:.:|...|..:||..|||. ||:... |..:
  Rat   272 AITNILDAELIRQWKSNMTRLPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTS-LSDQ 335

  Fly   305 ESLFVSQIVHKAFIEINEVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDN-THGLL 368
            |.|.|:|.:.|..||:||.||.|:::||.:.:     ||..|.::. .:|.|.:.::.| |..:|
  Rat   336 EQLSVAQALQKVKIEVNESGTVASSSTAILVS-----ARMAPTEMV-LDRSFLFVVRHNPTETIL 394

  Fly   369 FAGHFI 374
            |.|..:
  Rat   395 FMGQLM 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	102/384 (27%)
Serpine1	NP_036752.2	serpin	29..402	CDD:476815	105/393 (27%)