DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Db and Serpinb5

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001347782.1	Gene:	Serpinb5 / 20724	MGIID:	109579	Length:	375	Species:	Mus musculus

Alignment Length:	377	Identity:	94/377 - (24%)
Similarity:	176/377 - (46%)	Gaps:	31/377 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLE-----AQQV 72
            ||:.|...||......||::||:.:..|.::.::||.  ..||.|:.:.|.|..::     .|.|
Mouse    11 FAVDLFKQLCERDPAGNILFSPICLSTSLSLAQVGTK--GDTANEIGQVLHFENVKDVPFGFQTV 73

  Fly    73 AESFGVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGS--EQAASIINK 135
            ......:...|.    ||:...||:.|.|....:|....::.:..:...:||..  |:....||.
Mouse    74 TSDVNKLSSFYS----LKLVKRLYIDKSLNPSTEFISSTKRPYAKELETVDFKDKLEETKGQINS 134

  Fly   136 WVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTR-VRMMH 199
            .::..|:...:||:....::..:::.:||..:|.|:|...|.|.||:|..|..|...|: |:||:
Mouse   135 SIKELTDGHFEDILSENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRISKTDTKPVQMMN 199

  Fly   200 VCENFFFAVLPMFEATALRMNYSACNLAMIILLP----DEKSNLTSLEKKLSDISL--EVVSSAM 258
            :...|....:.......:.:.:...:|:|:|:||    ||.:.|..:|::|:..:|  ....|.|
Mouse   200 LEATFCLGNIDDISCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEQQLNPETLLQWTNPSTM 264

  Fly   259 NLEKVDVKIPSFTAEFQQELSQVLMLMGMNRIFS-GQAELGGMLQSEESLFVSQIVHKAFIEINE 322
            ...||.:.:|.|..|...:....|..:|:..:|: ..::..||.:: :.:.:|.::|:..:||.|
Mouse   265 ANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSET-KGVSLSNVIHRVCLEITE 328

  Fly   323 VGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDN-THGLLFAGHF 373
            .|.|:.....:    |.:..:.    .|:|:.||.|.|:.| |..::|.|.|
Mouse   329 DGGESIEVPGS----RILQHKD----EFNADHPFIYIIRHNKTRNIIFFGKF 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	93/375 (25%)
Serpinb5	NP_001347782.1	maspin_like	4..375	CDD:239012	94/377 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930