DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Serpine2

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_033281.1	Gene:	Serpine2 / 20720	MGIID:	101780	Length:	397	Species:	Mus musculus

Alignment Length:	361	Identity:	101/361 - (27%)
Similarity:	183/361 - (50%)	Gaps:	36/361 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAESFGVVLKSYEQCQVLKMAN 93
            |::.||..|.....||::| ::|. |.|::...:|:......:|.:.....:.|.:...::.:||
Mouse    50 NVVVSPHGIASILGMLQLG-ADGK-TKKQLSTVMRYNVNGVGKVLKKINKAIVSKKNKDIVTVAN 112

  Fly    94 GLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAAS-IINKWVESQTNNLIKDIIGPRVLTKD 157
            .:::..|.:::..|....:..|:.:...::|....:|| .||.||:::|..:|.:::.|.::...
Mouse   113 AVFLRNGFKMEVPFAVRNKDVFQCEVQNVNFQDPASASESINFWVKNETRGMIDNLLSPNLIDGA 177

  Fly   158 -SRLCLVNGIHFKGEWSISFNEKETREEDFFGSD-RPTRVRMMHVCENFFFAVLPMFEATALR-- 218
             :||.|||.::|||.|...|..:.|::..|...| :..:|.|:        |.|.:|.:.:.|
Mouse   178 LTRLVLVNAVYFKGLWKSRFQPESTKKRTFVAGDGKSYQVPML--------AQLSVFRSGSTRTP 234

  Fly   219 ---------MNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNL---EKVDVKIPSFT 271
                     :.|...:::|:|.||.|.|  |.|...:..|:.:.:.|.||.   :::.:.:|.||
Mouse   235 NGLWYNFIELPYHGESISMLIALPTESS--TPLSAIIPHITTKTIDSWMNTMVPKRMQLVLPKFT 297

  Fly   272 AEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAAATAAVAT 336
            |..|.:|.:.|..:|:..:|.........:...|||.||.|:.||.||::|.||:|:|||.|:
Mouse   298 AVAQTDLKEPLKALGITEMFEPSKANFTKITRSESLHVSHILQKAKIEVSEDGTKASAATTAI-- 360

  Fly   337 FRSMPARQGPPKVFHANRPFFYAIKDN-THGLLFAG 371
               :.||..|| .|..:|||.::|:.| |..:||.|
Mouse   361 ---LIARSSPP-WFIVDRPFLFSIRHNPTGAILFLG 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	101/361 (28%)
Serpine2	NP_033281.1	serpinE2_GDN	21..395	CDD:381039	101/361 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030