DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Db and Serpinf2

DIOPT Version :9

Sequence 1:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	379	Identity:	98/379 - (25%)
Similarity:	174/379 - (45%)	Gaps:	44/379 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AQGLEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFG-GLEAQ 70
            ||.:..|...|...:.:.|...|::.||||:.::.:.|.:|..  :.|...:...|... |....
Mouse    83 AQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQ--NQTLHSLHRVLHMNTGSCLP 145

  Fly    71 QVAESFGVVLKSYEQC--QVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAASII 133
            .:...|      |:..  ..:::|..:|:.||..:.:.|....|:.|.:||:::....|:..:.|
Mouse   146 HLLSHF------YQNLGPGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLTGKQEEDLANI 204

  Fly   134 NKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDR--PTRVR 196
            |:||:..|...|:|.:..  |...:.|.|:|.|||.|.|...|:...| ::|||..|.  ...|.
Mouse   205 NQWVKEATEGKIEDFLSE--LPDSTVLLLLNAIHFHGFWRTKFDPSLT-QKDFFHLDERFTVSVD 266

  Fly   197 MMHVCE---NFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAM 258
            |||...   .:|....|..:........   |::.::::|      |..|..:|::...:....:
Mouse   267 MMHAVSYPLRWFLLEQPEIQVAHFPFKN---NMSFVVVMP------TYFEWNVSEVLANLTWDTL 322

  Fly   259 ---NLEKVDVKI--PSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFI 318
               :|::...|:  |....:.|.:|...|..:|:..:|.| .:|.|:  ||::|.||.:.|::.:
Mouse   323 YHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELFQG-PDLRGI--SEQNLVVSSVQHQSTM 384

  Fly   319 EINEVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDNTHGL-LFAG 371
            |::|.|.||||||:......|:.:       |..||||.:.|.::|.|: ||.|
Mouse   385 ELSEAGVEAAAATSVAMNRMSLSS-------FTVNRPFLFFIMEDTIGVPLFVG 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	96/374 (26%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	98/379 (26%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010