DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42Db and Serpinc1

DIOPT Version :9

Sequence 1:NP_610244.2 Gene:Spn42Db / 35599 FlyBaseID:FBgn0033112 Length:388 Species:Drosophila melanogaster
Sequence 2:NP_543120.1 Gene:Serpinc1 / 11905 MGIID:88095 Length:465 Species:Mus musculus


Alignment Length:390 Identity:118/390 - (30%)
Similarity:199/390 - (51%) Gaps:38/390 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 EFAQGLEQFALCLHDHLCRA-SAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLE 68
            |.::...:||...:.||..: :...||..|||||..:.||.::|..  :.|.|::.|..:|..:.
Mouse    83 ELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGAC--NDTLKQLMEVFKFDTIS 145

  Fly    69 ---AQQVAESFGVVLKSYEQCQV---------LKMANGLYVMKGLQVDEQFGHILEQKFRSKPME 121
               :.|:...|..:     .|::         |..||.|:..|.|..:|.:..:.|..:.:|...
Mouse   146 EKTSDQIHFFFAKL-----NCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQP 205

  Fly   122 IDF--GSEQAASIINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREE 184
            :||  ..||:...||.||.::|...|||:|....:.:.:.|.|||.|:|||.|...|:.:.||:|
Mouse   206 LDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKE 270

  Fly   185 DFFGSD-RPTRVRMMHVCENFFFAVLPMFEAT-ALRMNYSACNLAMIILLPDEKSNLTSLEKKLS 247
            .|:..| :...|.||:  :...|....:.|.| .|.:.:...::.|:::||..:.:|..:|::|:
Mouse   271 PFYKVDGQSCPVPMMY--QEGKFKYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEQELT 333

  Fly   248 DISLEVVSSAMNLEKVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQ-AELGGMLQ-SEESLFVS 310
            ...|:.....::...:.|.:|.|..|....|.:.|..||:..:||.: ::|.|::. ..:.|:||
Mouse   334 PELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVS 398

  Fly   311 QIVHKAFIEINEVGTEAAAATAAVATFRSMPARQGPPKV-FHANRPFFYAIKD---NTHGLLFAG 371
            ...||||:|:||.|:||||:|:.|.|.||:    .|.:| |.|||||...|::   ||  ::|.|
Mouse   399 DAFHKAFLEVNEEGSEAAASTSVVITGRSL----NPNRVTFKANRPFLVLIREVALNT--IIFMG 457

  Fly   372  371
            Mouse   458  457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DbNP_610244.2 SERPIN 12..373 CDD:238101 117/383 (31%)
Serpinc1NP_543120.1 serpinC1_AT3 71..464 CDD:381002 118/390 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
65.990

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