DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9447 and Oacyl

DIOPT Version :9

Sequence 1:	NP_610243.4	Gene:	CG9447 / 35597	FlyBaseID:	FBgn0033110	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_001099609.1	Gene:	Oacyl / 291549	RGDID:	1304731	Length:	676	Species:	Rattus norvegicus

Alignment Length:	723	Identity:	159/723 - (21%)
Similarity:	254/723 - (35%)	Gaps:	217/723 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QLDDYDLCLDNQA------GTYCLVYVEILPNASSALWHQIDQVSQDSKHRFRHDRVFRGVCL-E 63
            :|..|..||..|:      |.||.::  ||.:.:.   :.:                  |||: :
  Rat    68 RLGSYSECLSTQSPEGSFRGQYCKLH--ILQDGTD---YSV------------------GVCVPD 109

  Fly    64 SCKQRINHLSEFREYEKEEILDKELISYYDKVHRRDA--MNSDRDLFNKEVVKGCLNQKFSEKFS 126
            ||.:.                |...:|..|.:..|:.  :.....||.|:....|
  Rat   110 SCAEE----------------DVTTMSQLDILRFRNTSFLEPSLSLFTKDSSSSC---------- 148

  Fly   127 LRTRSLIEYCVSASDKDLKMDLLDLAFYGILVVILFITLCSSFL-----------DYRL-----S 175
                .::..|.:.:   ||.|:..       .|.|||||....|           |:.|     |
  Rat   149 ----EIVARCAAGA---LKPDMFS-------SVCLFITLLGLVLPVAGTVYMVARDWGLDLKAAS 199

  Fly   176 KMNSQKS-ESFYREPLMDRRQRLLTS---------------------------FSVVRNYHRLVE 212
            ...:..| ||.....:...|||..||                           ||..:|...:..
  Rat   200 VCGTPTSLESLPLGNMESNRQRNRTSCQVQLPPPGPPSRGKRFLGALDGVLQCFSWQKNMPAICN 264

  Fly   213 PYNSDFSRDVSFFDGFRVIGVFVVILGHTLMVFMTVPIENPEFFEQFLFRFETSIFQNG------ 271
            |...  .......:|.||:.:..:|.|||..:...:.::|       :..::..:.:|.
  Rat   265 PELP--GGTCQTLNGIRVLSLLWIISGHTSQMTAWLSLDN-------VLEWKARVPKNPLYLYSR 320

  Fly   272 ----SLVIQIFFVMSGFLLYVKFTKRQQ-----IQPKTGTLECIAVYFRVFSYRYFRLLPSLLAL 327
                .|.:..||::||:|....|.|..|     |.||        |..|.|..|:.|    |..|
  Rat   321 SGPFYLGVDTFFLISGWLSARSFLKMHQNTSTGITPK--------VILRYFLKRFTR----LQLL 373

  Fly   328 ILFNGTLLVRLQN----GPFWRHLTEAERVFCRANWWKNVFFVTNHM-LEDSCSHQTWYLGADMQ 387
            .|::..|||...:    ||.| .:.:.....||..||.|:..:.|.: ::.:|:..||||.:|
  Rat   374 HLYSVCLLVGFFSFVPWGPVW-EVAQFHWDNCREVWWTNLLLLNNFLSVQKACNGWTWYLASD-- 435

  Fly   388 LFELFLIVIIITKKHPKLTRTIYTTLLALAFAVPAVLTYVLELDGIYHI-------RPETYRYLY 445
             |:..|:..:|...|.|..|.: ..|..|.|.|.:..|.:|.:  .|.:       ..|....||
  Rat   436 -FQFHLMTPLIFLVHGKSKRAL-VLLGGLLFLVSSTATALLTV--AYKLPVSSPSAASENETVLY 496

  Fly   446 FRHSDTFYQMYPPFYTNLGGYLFGFLCGHFYLRQRSGNV------ELLGHLKYDLAMWLLVLATL 504
            |.      :.|...|...|.:|.|.....|.......:|      .:||        |...|.||
  Rat   497 FS------EYYTKPYCRCGPFLVGLFLSMFMHSDHPTDVLRTKVQAVLG--------WAFSLTTL 547

  Fly   505 -GVLFSGYIFIRQDFAKP--SLWLALYAGIHKILWVLICAGFVILMCRK-VGG-----IAYDFCT 560
             .|:...|:.   |...|  |:..|:|..:|:.||. ...|:||..|:: .||     ::.....
  Rat   548 FAVVALAYVV---DDTSPTSSVLAAIYQALHRTLWA-AAVGWVIFACQEGFGGPVKRLLSCGIWA 608

  Fly   561 LPAFRPLARISFQSFLWHIVVLRTVAGNFRQPVYVSSFFLLCNVFSVF----ILTQFVAALVAVL 621
            ||     |.||:..:|.|.:|:....|.....::.:.    .|:|.:|    :||......:.:.
  Rat   609 LP-----ASISYACYLVHPIVIILYNGLQETLIHYTD----TNMFYLFSGHCVLTFLCGLALTLF 664

  Fly   622 LEYPFVEV 629
            :|.|:.|:
  Rat   665 IERPWQEL 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9447	NP_610243.4	Acyl_transf_3	222..611	CDD:280013	105/434 (24%)
CG9447	NP_610243.4	OafA	225..631	CDD:224748	110/451 (24%)
Oacyl	NP_001099609.1	NRF	44..136	CDD:214781	19/106 (18%)
		OafA	275..674	CDD:224748	110/451 (24%)
		Acyl_transf_3	275..663	CDD:280013	107/440 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910