DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9447 and oac-3

DIOPT Version :9

Sequence 1:	NP_610243.4	Gene:	CG9447 / 35597	FlyBaseID:	FBgn0033110	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_506446.2	Gene:	oac-3 / 182290	WormBaseID:	WBGene00007361	Length:	691	Species:	Caenorhabditis elegans

Alignment Length:	712	Identity:	163/712 - (22%)
Similarity:	286/712 - (40%)	Gaps:	151/712 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 YVEILPNASSAL--W-HQIDQVSQDSKHRFRHDRVFRGVC----LESCKQRINHLSEFREYEK-- 80
            |..:.|..:..:  | ..|:|.:..|.     |.:|...|    |...|..|..:.::..:.|
Worm    40 YSHVTPECTKDMKTWISSIEQFTAASS-----DCLFFKNCTASILNILKDNIYAIQQYDAFAKIP 99

  Fly    81 -EEILDKELI--SYYDKVHR------------------RDAMNSDRDL--------FNKEVV--K 114
             ..:|:..|:  ..|.:.||                  |:|..|...:        |.:.|.  |
Worm   100 SAGLLEVSLVFDGSYQECHRISGVKYETNYCYVLLVPGRNANCSGGSIQNAGTSVAFRRAVCMPK 164

  Fly   115 GCLNQK----FSEKFSLRTRSLIEYCVSASDKDLKMDLLDLAFYGILVVILFITLCSSFLD---- 171
            .|.:..    :::..:|...:...:|   |.:|:..|.....|...:.||:...:.::.:|
Worm   165 SCASSDTVDLYNQLSALPLTACATFC---SQRDVPKDSAFWGFSAFMFVIVSTVILATTVDYLRE 226

  Fly   172 --YRLSKMNSQKSESFYREPLMDRRQRLLTSFSVVRNYHRLVEPYNSDFSRDVSFFDGFRVIGVF 234
              |.:|..:.:||.|.|         |||.|||...|...::. .:|..:..:...|..|.:.:.
Worm   227 SVYDISSKSIEKSASLY---------RLLYSFSFWTNASTILN-VSSQPATHIKCLDCIRGLSMA 281

  Fly   235 VVILGHTLMVF----MTVPIENPEFFEQFLFRFETSIFQNGSLVIQIFFVMSGFLLYVKFTKRQQ 295
            .|:.||.|..|    ..:||::      |...|....|.|....:..||::||..:...|.:
Worm   282 WVLSGHMLNYFAFADTLMPIKS------FANYFADYFFMNAVFSVDTFFLVSGITVAYSFFR--- 337

  Fly   296 IQPKTGTLECIAVYFRVFSYRYFRLLPSLLALILFNGTLLVRLQNGPFWRHL---TEAERVFCRA 357
            ::|.|.||:..|.:...:.:||.||.|..:..|.|.....:.:| ||....|   |..:...|:|
Worm   338 LKPTTKTLKSPATWILFYVHRYVRLTPPYIIFIGFYAVYALYIQ-GPLAASLFNFTVLQVEACKA 401

  Fly   358 NWWKNVFFVTN-HMLEDSCSHQTWYLGADMQLFELFLIVIIITKKHPKLTRTIYTTLLALAFAV- 420
            :||:|:.::.| ...|:.|...:|||..|.|   |:|:..|:      |....:|.:..|..::
Worm   402 SWWRNLIYINNFDNGENPCYGPSWYLAVDTQ---LYLVAPIL------LVALTWTPIAGLVVSMV 457

  Fly   421 ----PAVLTYVLELDGIYHIRPETYRYLYF-RHSDTF---------YQMYPPFYTNLGGYLFGFL 471
                ..::.::|              |..| ..:|:|         :.:|...:|....||.|.|
Worm   458 GCIGSMIIVFIL--------------YQKFDMPADSFNADSSGKFNFYVYQKPWTRCPPYLVGIL 508

  Fly   472 CGHFYLRQRSGNVELLGHLKYDLAMWLLVLATLGVLFS------GYIFIRQDFAKPSLWL-ALYA 529
            .|:|..|..:..|: |..:|..:.|.|.|    |::|:      ||    ......|.|. |.|.
Worm   509 GGYFLSRFATSPVK-LSFVKKLIPMLLAV----GLIFACLTANIGY----DQGDHWSSWTKATYY 564

  Fly   530 GIHKILWVLICAGFVILMCRK--VGGIAYDFCTLPAFRPLARISFQSFLWHIVVLRTVAGNFRQP 592
            ...:..|.|... ::||.|..  .|.|. :|.:.|.::||.|:|:.:::.|::|:........:|
Worm   565 NFSRFFWALSVL-WIILSCHYGWAGPIG-NFMSHPIWQPLGRLSYSAYIVHLMVVYYFLNVGDKP 627

  Fly   593 V-YVSSF-FLLCNVFSVFILTQFVAALVAVLLEYPFVE----VLRCLIKPEKGPE-EVGPEI 647
            : :||:: ..:..:....|||...|...:.|.|.|.|:    :|..|::.::.|| :.|.||
Worm   628 LHFVSTWQVYVYYILPATILTYIFAFFWSCLFEIPVVKLEKFLLEILLRKKRLPEKKTGKEI 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9447	NP_610243.4	Acyl_transf_3	222..611	CDD:280013	101/422 (24%)
CG9447	NP_610243.4	OafA	225..631	CDD:224748	108/443 (24%)
oac-3	NP_506446.2	NRF	85..191	CDD:214781	16/108 (15%)
oac-3	NP_506446.2	Acyl_transf_3	269..653	CDD:376607	103/427 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910