DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment coro and RIB7

DIOPT Version :9

Sequence 1:	NP_001260743.1	Gene:	coro / 35596	FlyBaseID:	FBgn0265935	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_009711.3	Gene:	RIB7 / 852450	SGDID:	S000000357	Length:	244	Species:	Saccharomyces cerevisiae

Alignment Length:	261	Identity:	51/261 - (19%)
Similarity:	81/261 - (31%)	Gaps:	92/261 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 CAVNPKFLAIIVESAGGGAFIVLPHNKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDC 104
            |...|:||...:.:||               ..::.:|     |.:.:.:....|..::.|.
Yeast     7 CEDLPQFLQNYLPNAG---------------QTENTIV-----PFVTLTYAQSLDARVSRGP--- 48

  Fly   105 VVKVWQIPDGGLSRTLTEPVVDLVFHQRR---------VGLVL---------WHPSALNVLLTAG 151
                      |:..|::.|....:.|..|         .|.||         |.|..     .|.
Yeast    49 ----------GVRTTISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKWGPDP-----AAN 98

  Fly   152 SDNQVVI-----WNVGTG---EILVHIDSHPDIV--------------YSACFNWDGSKLVTTCK 194
            |...::|     |.....   |:.:.....|.||              |:.|...|.:|||
Yeast    99 SPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQHVDYAICPINDTTKLV---- 159

  Fly   195 DKKIRIYDPRTAELE-SEAMCHEGSKATRAIFLR----HGLIFTTG--FNRSSERQYSLRAPDAL 252
            |.| ::::....|.. ...|...|:.....:.||    :.||.|.|  |..||..:.|  .|..:
Yeast   160 DWK-KLFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSLIITIGSTFLGSSGTEVS--PPQTV 221

  Fly   253 N 253
            |
Yeast   222 N 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	DUF1899	7..64	CDD:286094	6/23 (26%)
		WD40 repeat	37..78	CDD:293791	6/37 (16%)
		WD40	79..294	CDD:295369	44/222 (20%)
		WD40 repeat	85..129	CDD:293791	5/43 (12%)
		WD40 repeat	134..171	CDD:293791	10/53 (19%)
		WD40 repeat	178..213	CDD:293791	9/35 (26%)
		WD40 repeat	220..260	CDD:293791	12/40 (30%)
		WD40 repeat	267..308	CDD:293791
		WD40_4	343..385	CDD:292916
RIB7	NP_009711.3	ribD_Cterm	28..241	CDD:129330	45/225 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1985
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900