Protein Alignment coro and coro2ba

DIOPT Version :10

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_688721.4
• Gene: coro2ba / 560235
• ZFINID: ZDB-GENE-050518-1
• Length: 491
• Species: Danio rerio
• Alignment Length: 520
• Identity: 215/520 - (41%)
• Similarity: 318/520 - (61%)
• Gaps: 56/520 - (10%)

  Fly     1 MSFR-VVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPH 64
            ||:| ..||||||:|||:...||.|::.|.::|:..|:.|||||.|||||:.||||||:|:|:|.
Zfish     6 MSWRPTYRSSKFRNVYGKVANREHCFEGIPITKNVHDNHFCAVNAKFLAIVTESAGGGSFVVIPV 70

  Fly    65 NKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVF 129
            .:.|||...:|.|.||:|.||||.|.|.:||:|||.|||..|::|:|||.||:|:|||.|::|..
Zfish    71 TQFGRIDPHYPKVCGHQGNVLDIKWNPFHDNIIASCSEDSSVRIWEIPDSGLTRSLTESVLELYG 135

  Fly   130 HQRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDSHPDIVYSACFNWDGSKLVTTCK 194
            |.|||||:.|||:...:|.:||.|.:::|||:..||.:..||.|.|::....||.:||.|.|:||
Zfish   136 HSRRVGLIEWHPTTSGILFSAGYDYKILIWNLEIGEPVKMIDCHSDVILCMSFNTEGSLLATSCK 200

  Fly   195 DKKIRIYDPRTAELESEAMCHEGSKATRAIFLRH-GLIFTTGFNRSSERQYSLRAPDALNEPIVM 258
            |||:|:.:||:..:..||. .:..|..|.:||.: ..:.|||.:|.:.||.:|...:.|:.||:.
Zfish   201 DKKLRVIEPRSGRVLQEAN-FKNHKVNRVVFLGNIKRLLTTGVSRWNTRQIALWDQEDLSMPIIE 264

  Fly   259 VELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRG 323
            .|:|..:|::||.|||||:|:||.||||..|||:|||.|.|::.|:..|::..||:|:|:|||.|
Zfish   265 EEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEVTLEKPYLQYLMEFRSPAPQKGLGVMPKHG 329

  Fly   324 CDVTTCEVAKFYRM-NNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPIT 387
            .||..|||.:||:: ...||.:.|||.|||:|:.:|||:||.|...:.|::|:||:.|.:..|:.
Zfish   330 LDVGACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALSADEWLSGINRGPVL 394

  Fly   388 FSLKDRVSIVQGGY--VSSSVNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGNFASGNNNEAS 450
            .|||:       ||  .:..|.|:...:|.|.::                         |..:..
Zfish   395 MSLKE-------GYNRPNKLVFKAPVKEKKGGVV-------------------------NGIDLL 427

  Fly   451 EGGPPAAVLSEKDLRTI----QDEIRKLKAIIVKQENRIRALEAK-----------EDARNKNGS 500
            |..||.   :|.:|..:    |:|:|:||..:.:::.:||.||.:           .:..|.|||
Zfish   428 ENVPPR---TENELLRMFFRQQEELRRLKDELTQKDIKIRQLELELNNIRNSPNINNNNNNSNGS 489

  Fly   501  500
            Zfish   490  489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	WD40	9..>392	CDD:475233	184/384 (48%)
		WD40 repeat	37..78	CDD:293791	23/40 (58%)
		WD40 repeat	85..129	CDD:293791	26/43 (60%)
		WD40 repeat	134..171	CDD:293791	15/36 (42%)
		WD40 repeat	178..213	CDD:293791	15/34 (44%)
		WD40 repeat	220..260	CDD:293791	13/40 (33%)
		WD40 repeat	267..308	CDD:293791	23/40 (58%)
coro2ba	XP_688721.4	None