DRSC/TRiP Functional Genomics Resources

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Protein Alignment coro and coro1ca

DIOPT Version :10

Sequence 1:NP_001260743.1 Gene:coro / 35596 FlyBaseID:FBgn0265935 Length:535 Species:Drosophila melanogaster
Sequence 2:NP_958452.1 Gene:coro1ca / 317741 ZFINID:ZDB-GENE-030114-6 Length:474 Species:Danio rerio


Alignment Length:488 Identity:270/488 - (55%)
Similarity:344/488 - (70%) Gaps:27/488 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 RVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVG 68
            ||||.||||||:|||:|.:||||:||||:.:|||.||||||||:|:|||::|||||:|||.:|.|
Zfish     4 RVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVALIVEASGGGAFMVLPLHKTG 68

  Fly    69 RIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFHQRR 133
            ||...:|.|.||.||||||.||||||.|||||||||.|.|||||:.||..:::||||.|..|.:|
Zfish    69 RIDKAYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLVTSMSEPVVVLEGHSKR 133

  Fly   134 VGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHI-DSHPDIVYSACFNWDGSKLVTTCKDKK 197
            ||:|.|||:|.||||:||.||.::||||||||.::.: |.||||:||.|:|.:||.:.|.|||||
Zfish   134 VGVVTWHPTARNVLLSAGCDNMIIIWNVGTGESMITLEDHHPDIIYSVCWNRNGSLICTACKDKK 198

  Fly   198 IRIYDPRTAELESEA-MCHEGSKATRAIFLRHGLIFTTGFNRSSERQYSLRAPDALNEPIVMVEL 261
            ||:.|||..|:.:|. ..|||::..|||||..|.:|||||:|.||||.:|..|:.::||:.:.|:
Zfish   199 IRVIDPRKEEIIAEKDKAHEGARPMRAIFLSDGKVFTTGFSRMSERQLALWDPENIDEPVAVHEM 263

  Fly   262 DTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCDV 326
            ||||||:.|.||.|||::||||||||.|||||:|.|.|||||:|||.|.|||||:|.|||||.||
Zfish   264 DTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPFVHYLNTFTTKEPQRGMGYMPKRGLDV 328

  Fly   327 TTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITFSLK 391
            ..||:|:||:::.. .|:.|.|||||||||||:||||||...||.:.||||.:||:.||:..|||
Zfish   329 NKCEIARFYKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPDAPLEAEEWFEGKNGDPVLISLK 392

  Fly   392 DRVSIVQGGYVSSSVNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGNFASGNNNEASEGGPPA 456
            .       ||:... |:.|...|. |||     |:..|..|.::......|:..          .
Zfish   393 H-------GYIPGK-NRDLKVVKK-NIL-----DNKMSKNTENTTPAHKTATST----------P 433

  Fly   457 AVLSEKDLRTIQDEIRKLKAIIVKQENRIRALE 489
            ::.||..|..:..||:.|:.::..||.||..||
Zfish   434 SIKSEAKLEEVLKEIKSLRELVSSQEKRIGKLE 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
coroNP_001260743.1 WD40 9..>392 CDD:475233 241/384 (63%)
WD40 repeat 37..78 CDD:293791 26/40 (65%)
WD40 repeat 85..129 CDD:293791 31/43 (72%)
WD40 repeat 134..171 CDD:293791 23/37 (62%)
WD40 repeat 178..213 CDD:293791 19/35 (54%)
WD40 repeat 220..260 CDD:293791 20/39 (51%)
WD40 repeat 267..308 CDD:293791 29/40 (73%)
coro1caNP_958452.1 WD40 9..471 CDD:475233 266/483 (55%)
WD40 repeat 37..79 CDD:293791 27/41 (66%)
WD 1. /evidence=ECO:0000255 79..119 31/39 (79%)
WD40 repeat 85..129 CDD:293791 31/43 (72%)
WD 2. /evidence=ECO:0000255 129..169 25/39 (64%)
WD40 repeat 134..171 CDD:293791 23/36 (64%)
WD 3. /evidence=ECO:0000255 173..212 22/38 (58%)
WD40 repeat 179..214 CDD:293791 19/34 (56%)
WD 4. /evidence=ECO:0000255 216..259 23/42 (55%)
WD40 repeat 222..262 CDD:293791 20/39 (51%)
WD 5. /evidence=ECO:0000255 264..304 29/39 (74%)
WD40 repeat 269..310 CDD:293791 29/40 (73%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 415..437 3/31 (10%)

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