Protein Alignment coro and Coro6

DIOPT Version :9

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_006533001.1
• Gene: Coro6 / 216961
• MGIID: 2183448
• Length: 472
• Species: Mus musculus
• Alignment Length: 496
• Identity: 263/496 - (53%)
• Similarity: 342/496 - (68%)
• Gaps: 42/496 - (8%)

  Fly     1 MSFRVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHN 65
            ||.||||.||||||:|||.|.:|.|::|||||.:|||.||||||||||||||:.|||||||||..
Mouse     1 MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLA 65

  Fly    66 KVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFH 130
            |.||:..::|||.||.||||||.|||||||||||.|:|..|.||||||....|.:||||:.|..|
Mouse    66 KTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGH 130

  Fly   131 QRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDS-HPDIVYSACFNWDGSKLVTTCK 194
            .:|||::.|||:|.||||:||.||.::||||||||:|:.:|. |||:::|.|:|.:||.|.||||
Mouse   131 SKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCK 195

  Fly   195 DKKIRIYDPRTAELESE-AMCHEGSKATRAIFLRHGLIFTTGFNRSSERQYSLRAPDALNEPIVM 258
            ||.:||.|||.:::.:| |..|||::..||:|...|.:.:|||:|.||||.:|..|:...||:.:
Mouse   196 DKTLRIIDPRKSQVVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVAL 260

  Fly   259 VELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRG 323
            .|:||||||:.|.||.|::::||||||||.|||||:|.|||||||:|||.:.|||||:|.|||||
Mouse   261 QEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRG 325

  Fly   324 CDVTTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITF 388
            .||:.||:|:||:::.. .|:.|.|||||||||||:||||||...:.|:.|:||:.|:||:|:..
Mouse   326 LDVSKCEIARFYKLHER-KCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLI 389

  Fly   389 SLKDRVSIVQGGYVSSSVNKSLPAKKAGNILN-----KPRGDSASSGATSSSAGGGNFASGNNNE 448
            |||:       |||.....:....|:  |||:     .||...::|.|..|
Mouse   390 SLKE-------GYVPPKHRELRVTKR--NILDVRPPASPRRSQSASEAPLS-------------- 431

  Fly   449 ASEGGPPAAVLSEKDLRTIQDEIRKLKAIIVKQENRIRALE 489
                       .:..|.|:.:||:.|:..:..||.||.|||
Mouse   432 -----------QQHTLETLLEEIKALRDRVQAQEERITALE 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	DUF1899	7..64	CDD:286094	43/56 (77%)
		WD40 repeat	37..78	CDD:293791	29/40 (73%)
		WD40	79..294	CDD:295369	124/216 (57%)
		WD40 repeat	85..129	CDD:293791	29/43 (67%)
		WD40 repeat	134..171	CDD:293791	23/36 (64%)
		WD40 repeat	178..213	CDD:293791	18/35 (51%)
		WD40 repeat	220..260	CDD:293791	16/39 (41%)
		WD40 repeat	267..308	CDD:293791	28/40 (70%)
		WD40_4	343..385	CDD:292916	26/41 (63%)
Coro6	XP_006533001.1	WD40	9..466	CDD:392136	257/488 (53%)
		WD40 repeat	37..79	CDD:293791	30/41 (73%)
		WD40 repeat	85..129	CDD:293791	29/43 (67%)
		WD40 repeat	134..171	CDD:293791	23/36 (64%)
		WD40 repeat	179..215	CDD:293791	18/35 (51%)
		WD40 repeat	222..262	CDD:293791	16/39 (41%)
		WD40 repeat	269..310	CDD:293791	28/40 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845455
Domainoid	1	1.000	174	1.000	Domainoid score	I3658
eggNOG	1	0.900	-	-		E1_COG1985
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	531	1.000	Inparanoid score	I1199
Isobase	1	0.950	-	0	Normalized mean entropy	S944
OMA	1	1.010	-	-		QHG53996
OrthoDB	1	1.010	-	-		D179930at33208
OrthoFinder	1	1.000	-	-		FOG0000390
OrthoInspector	1	1.000	-	-		otm43590
orthoMCL	1	0.900	-	-		OOG6_100479
Panther	1	1.100	-	-	O	PTHR10856
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R238
SonicParanoid	1	1.000	-	-		X216
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750