Protein Alignment coro and Coro2a

DIOPT Version :9

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_849224.2
• Gene: Coro2a / 107684
• MGIID: 1345966
• Length: 543
• Species: Mus musculus
• Alignment Length: 516
• Identity: 200/516 - (38%)
• Similarity: 314/516 - (60%)
• Gaps: 45/516 - (8%)

  Fly     7 RSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVGRIA 71
            ||||||||||:...:|.|||::.:::|..|:.||||||.|:|::.|.||||||:|:|.::.|::.
Mouse    27 RSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLD 91

  Fly    72 ADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFHQRRVGL 136
            ..:|.|.||:|.||||.|.|.||..|||.|||..:|:|.||...|:|.||....:|:.|.|||||
Mouse    92 PHYPKVCGHRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELIGHARRVGL 156

  Fly   137 VLWHPSALNVLLTAGSDNQVVIWNVGTGEILV-----HIDSHPDIVYSACFNWDGSKLVTTCKDK 196
            |.|||:..|:|.:||.|.:|::||:.|.:.::     .|:.|.|::.|..||.:||.|.|||||:
Mouse   157 VEWHPTTANILFSAGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDR 221

  Fly   197 KIRIYDPRTAELESEAMCHEGSKATRAIFLRH-GLIFTTGFNRSSERQYSLRAPDALNEPIVMVE 260
            ||||.|||...:..|| .::|.:|.:.:||.. ..:.:||.:|.:.||.:|...:.|:.|:...:
Mouse   222 KIRIVDPRLGIVLQEA-SYKGHRANKVLFLGSLKKLLSTGTSRWNNRQMALWDQENLSVPLTEED 285

  Fly   261 LDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCD 325
            ||.|:||:||.:|:||:|:|:.||||..|||:||:.|.|.:.|:..:::..||:|||:|||||.|
Mouse   286 LDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSMEKPHLTYLTEYRSYNPQKGIGIMPKRGLD 350

  Fly   326 VTTCEVAKFYRM-NNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITFS 389
            |::||:.:||:: ....|.:.:||.|||:|:.:|||:||.|.|...::||.||:.|.:..||..|
Mouse   351 VSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSGMNRGPIMMS 415

  Fly   390 LKDRVSIVQGGYVSSSVNKSLPAKK--AGNILN------KPRGDSASSGA--------------T 432
            |:....::.        :::||.::  :.:::.      :|....|..|.              |
Mouse   416 LRPGSELLD--------SQTLPPERPLSNSMVQVSPQPLEPMKQPAEDGDQAPFSLLEEKLAKWT 472

  Fly   433 SSSAGGGNFASGNNNEASEGGPPAAVLSEKDLRTI----QDEIRKLKAIIVKQENRIRALE 489
            :....|......|..:..|..||.   :|.:|..:    |:|||:|:.:::::|.:.:.||
Mouse   473 AEHHLGEKSCLTNGFDVFECSPPK---TENELLQMFYRQQEEIRRLRELLIQREVQTKQLE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	DUF1899	7..64	CDD:286094	32/56 (57%)
		WD40 repeat	37..78	CDD:293791	19/40 (48%)
		WD40	79..294	CDD:295369	99/220 (45%)
		WD40 repeat	85..129	CDD:293791	22/43 (51%)
		WD40 repeat	134..171	CDD:293791	16/41 (39%)
		WD40 repeat	178..213	CDD:293791	19/34 (56%)
		WD40 repeat	220..260	CDD:293791	11/40 (28%)
		WD40 repeat	267..308	CDD:293791	20/40 (50%)
		WD40_4	343..385	CDD:292916	18/41 (44%)
Coro2a	NP_849224.2	WD40	29..536	CDD:392136	198/514 (39%)
		WD40 repeat	59..99	CDD:293791	20/39 (51%)
		WD40 repeat	105..149	CDD:293791	22/43 (51%)
		WD40 repeat	154..196	CDD:293791	16/41 (39%)
		WD40 repeat	203..238	CDD:293791	20/35 (57%)
		WD40 repeat	244..285	CDD:293791	11/40 (28%)
		WD40 repeat	292..331	CDD:293791	20/38 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845454
Domainoid	1	1.000	68	1.000	Domainoid score	I9687
eggNOG	1	0.900	-	-		E1_COG1985
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53996
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000390
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100479
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X216
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650