Protein Alignment koi and MPS3

DIOPT Version :10

• Sequence 1: NP_001260738.1
• Gene: koi / 35594
• FlyBaseID: FBgn0265003
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: NP_012515.4
• Gene: MPS3 / 853434
• SGDID: S000003556
• Length: 682
• Species: Saccharomyces cerevisiae
• Alignment Length: 530
• Identity: 99/530 - (18%)
• Similarity: 209/530 - (39%)
• Gaps: 162/530 - (30%)

  Fly   503 LELQSSGGWQDGAKLSQANLEEITKLIKAEVHLHESHYTIQLDRI------DFASLLERILAAPA 561
            ||..|||......| |.:||::....:.:|:...:..::.:||:.      .|...::|:|.: .
Yeast   180 LESHSSGATSSPGK-SFSNLQKQVNHLYSELSKRDEKHSSELDKTVKIIVSQFEKNIKRLLPS-N 242

  Fly   562 LADFVDARISLRVGELEPKESSGSSDAEVQIERLNREIAFIKLALSDKQAENADLHQ-SISNLKL 625
            |.:|                       |..|..|.:::..|..::|:.|..|   |: ::.|:..
Yeast   243 LVNF-----------------------ENDINSLTKQVETISTSMSELQRRN---HKFTVENVTQ 281

  Fly   626 GQEDLLERIQQHELSQD-----RRFHGLL--AEIENKLSALNDSQFALLNKQIKLSLVEILGFKQ 683
            .|:.|::::..| |.|:     .....||  .|:.|.||||               :.:::   :
Yeast   282 WQDQLVKQLDTH-LPQEIPVVINNSSSLLIIPELHNYLSAL---------------ISDVI---E 327

  Fly   684 STAGGSAGQLD---DFDLQTWVRSM------FVAKDYLEQQLLELNKRTNNNIRDEIERSSILLM 739
            |...|:||..:   ::||..:|:.:      ::.|||..|   |:|:|..:|.::        :.
Yeast   328 SPGIGTAGSAESRWEYDLNRYVKEILSNELQYIDKDYFIQ---EMNRRLQSNKQE--------IW 381

  Fly   740 SDISQRLKREILLVVEAKHNESTKALKGHIREEEVRQIVKTVL-AIYDADK---TGLVDFALESA 800
            .:|:.||:.:     :.:..:..:....::.::....::|.:: .||::::   ...:|||....
Yeast   382 EEITNRLETQ-----QQQQQQQVQQDYSNVPQQYSSILMKRLIHQIYNSNQHQWEDDLDFATYVQ 441

  Fly   801 GGQILSTRCTESYQ-----------TKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQGFP 854
            |.::|:...:.:::           |.|.|.|   ...|...|          :||..||
Yeast   442 GTKLLNHLTSPTWRQGSGVQPIELLTDSKQSS---STYWQCEN----------EPGCSWA----- 488

  Fly   855 GFLVLKLNSLVYVTGFTLEHIPKSLSPTGR-------IESAPRNFTVW-GLEQEKDQEPVL---- 907
                ::..:.:|:|..:..|        ||       :.||||..::: .|.|.|:.:.:.
Yeast   489 ----IRFKTPLYLTKISYMH--------GRFTNNLHIMNSAPRLISLYVKLSQTKEIKALQTLAN 541

  Fly   908 ---FGDYQFEDNG----ASLQYFAVQN------------LDIKRPYEIVELRIETNHGHPTYTCL 953
               ||.:...|..    |..:|....:            :.:|.....:..:::.|:|:..:..|
Yeast   542 QYGFGQHHKRDRNYIKIAKFEYRLTDSRIRQQMYLPPWFIQLKPLVRSIVFQVDENYGNKKFISL 606

  Fly   954 YRFRVHGKPP 963
            .:|.::|..|
Yeast   607 RKFIINGVTP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
koi	NP_001260738.1	PRK03918	<462..>653	CDD:235175	34/163 (21%)
		Sad1_UNC	827..962	CDD:400199	29/165 (18%)
MPS3	NP_012515.4	Sad1_UNC	478..615	CDD:474037	28/163 (17%)