DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment koi and SPAG4

DIOPT Version :9

Sequence 1:	NP_001260738.1	Gene:	koi / 35594	FlyBaseID:	FBgn0265003	Length:	965	Species:	Drosophila melanogaster
Sequence 2:	NP_003107.1	Gene:	SPAG4 / 6676	HGNCID:	11214	Length:	437	Species:	Homo sapiens

Alignment Length:	238	Identity:	75/238 - (31%)
Similarity:	119/238 - (50%)	Gaps:	15/238 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   730 EIERSSILLMSDISQRLK------REILLVVEAKHNE-STKALKGHIREEEVRQIVKTVLAIYDA 787
            |.|...:|.:|:..:|::      :::...::..|.| ||      :|.....::.|.|....:.
Human   193 ENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVST------VRAANSERVAKLVFQRLNE 251

  Fly   788 DKTGLVDFALESAGGQILSTRCTESYQTKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQG 852
            |.....|:||.|.|..|...:.:..|..::..........|.....|.|.:.|:|.||.||||:|
Human   252 DFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNCWAFEG 316

  Fly   853 FPGFLVLKLNSLVYVTGFTLEHIPKSLSPTGRIESAPRNFTVWGLEQEKDQEPVLFGDYQFEDNG 917
            ..|.:|::|...|.::..||:|.|.|:..||...||||:|.|:|| |..|:..|..|.:.|:...
Human   317 DQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGL-QVYDETEVSLGKFTFDVEK 380

  Fly   918 ASLQYFAVQNLDIKRPYEIVELRIETNHGHPTYTCLYRFRVHG 960
            :.:|.|.:|| |....:..|:::|.:|.|||.:|||||.|.||
Human   381 SEIQTFHLQN-DPPAAFPKVKIQILSNWGHPRFTCLYRVRAHG 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
koi	NP_001260738.1	Sad1_UNC	827..962	CDD:285038	55/134 (41%)
SPAG4	NP_003107.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..88
SPAG4	NP_003107.1	Sad1_UNC	291..422	CDD:311603	53/132 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1569602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12911
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X471
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020