DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SdhB and sdhb

DIOPT Version :9

Sequence 1:	NP_477101.1	Gene:	SdhB / 35590	FlyBaseID:	FBgn0014028	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001092210.1	Gene:	sdhb / 562149	ZFINID:	ZDB-GENE-030131-8005	Length:	280	Species:	Danio rerio

Alignment Length:	278	Identity:	200/278 - (71%)
Similarity:	234/278 - (84%)	Gaps:	8/278 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LSRVGSLVARNQMRAISNGTAQLEQQAQPKEAQEPQIKKFEIYRWNPDNAGEKPYMQTYEVDLRE 74
            |||..|.|.|..:.|:     :..|.|....|| |:||||:||||:||..|:||.|||||:||..
Zfish     8 LSRCCSAVHRPAVTAV-----RFAQTAAAPAAQ-PRIKKFQIYRWDPDTVGDKPRMQTYEIDLNT 66

  Fly    75 CGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNIGGTNTLACISKIDINTSKSLKVYPLPH 139
            |||||||||||||||||.||||||||||||||||||||.|.|||||::|||.||||..|:|||||
Zfish    67 CGPMVLDALIKIKNEMDSTLTFRRSCREGICGSCAMNINGGNTLACLNKIDTNTSKVTKIYPLPH 131

  Fly   140 MYVVRDLVPDMNNFYEQYRNIQPWLQRKNEAGEKKGKAQYLQSVEDRSKLDGLYECILCACCSTS 204
            ||||:||||||:|||.||::|:|:|::|:|:  ::||.|||||||||.|||||||||||||||||
Zfish   132 MYVVKDLVPDMSNFYAQYKSIEPYLKKKDES--QQGKQQYLQSVEDRQKLDGLYECILCACCSTS 194

  Fly   205 CPSYWWNAEKYLGPAVLMQAYRWIIDSRDENSAERLNKLKDPFSVYRCHTIMNCTRTCPKGLNPG 269
            ||||||||:||||||||||||||:|||||:.:.:||:||:||||:||||||||||||||||||||
Zfish   195 CPSYWWNADKYLGPAVLMQAYRWMIDSRDDFTEDRLSKLQDPFSLYRCHTIMNCTRTCPKGLNPG 259

  Fly   270 RAIAEIKKLLSGLASKPA 287
            :|||||||::.....|.|
Zfish   260 KAIAEIKKMMVTYKQKDA 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SdhB	NP_477101.1	PLN00129	6..279	CDD:215067	198/268 (74%)
sdhb	NP_001092210.1	sdhB	40..271	CDD:235652	184/232 (79%)
		Fer2_3	40..146	CDD:289830	85/105 (81%)
		Fer4_17	184..257	CDD:290268	62/72 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580781
Domainoid	1	1.000	193	1.000	Domainoid score	I3156
eggNOG	1	0.900	-	-		E1_COG0479
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2255
Inparanoid	1	1.050	419	1.000	Inparanoid score	I1777
OMA	1	1.010	-	-		QHG54746
OrthoDB	1	1.010	-	-		D1264157at2759
OrthoFinder	1	1.000	-	-		FOG0003194
OrthoInspector	1	1.000	-	-		oto41104
orthoMCL	1	0.900	-	-		OOG6_100664
Panther	1	1.100	-	-	LDO	PTHR11921
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R309
SonicParanoid	1	1.000	-	-		X1851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800