DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SdhB and sdhb

DIOPT Version :9

Sequence 1:	NP_477101.1	Gene:	SdhB / 35590	FlyBaseID:	FBgn0014028	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001120000.1	Gene:	sdhb / 100144957	XenbaseID:	XB-GENE-970193	Length:	284	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	192/258 - (74%)
Similarity:	220/258 - (85%)	Gaps:	2/258 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AQLEQQAQPKEAQEPQIKKFEIYRWNPDNAGEKPYMQTYEVDLRECGPMVLDALIKIKNEMDPTL 94
            ||....|.|....|.:||||.||||:||..|:||.||||||||.|||.|||||||||||||||||
Frog    27 AQTAAAAAPASQAEARIKKFAIYRWDPDKPGDKPRMQTYEVDLNECGSMVLDALIKIKNEMDPTL 91

  Fly    95 TFRRSCREGICGSCAMNIGGTNTLACISKIDINTSKSLKVYPLPHMYVVRDLVPDMNNFYEQYRN 159
            ||||||||||||||||||.|.|||||..:||.|.||..|:|||||||||:|||||::|||.||::
Frog    92 TFRRSCREGICGSCAMNINGGNTLACTVRIDTNLSKVSKIYPLPHMYVVKDLVPDLSNFYAQYKS 156

  Fly   160 IQPWLQRKNEAGEKKGKAQYLQSVEDRSKLDGLYECILCACCSTSCPSYWWNAEKYLGPAVLMQA 224
            |:|:|::|:|:.|  ||.|||||:|||.|||||||||||||||||||||||||:|||||||||||
Frog   157 IEPYLKKKDESQE--GKEQYLQSIEDRDKLDGLYECILCACCSTSCPSYWWNADKYLGPAVLMQA 219

  Fly   225 YRWIIDSRDENSAERLNKLKDPFSVYRCHTIMNCTRTCPKGLNPGRAIAEIKKLLSGLASKPA 287
            |||:|||||:.:.|||.||:||||:||||||||||||||||||||:|||||||:::....:.|
Frog   220 YRWMIDSRDDYTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKERAA 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SdhB	NP_477101.1	PLN00129	6..279	CDD:215067	191/248 (77%)
sdhb	NP_001120000.1	PLN00129	42..275	CDD:215067	186/234 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3337
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2255
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1801
OMA	1	1.010	-	-		QHG54746
OrthoDB	1	1.010	-	-		D1264157at2759
OrthoFinder	1	1.000	-	-		FOG0003194
OrthoInspector	1	1.000	-	-		oto105309
Panther	1	1.100	-	-	LDO	PTHR11921
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R309
SonicParanoid	1	1.000	-	-		X1851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110