| Sequence 1: | NP_001097202.2 | Gene: | Epac / 35588 | FlyBaseID: | FBgn0085421 | Length: | 1006 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_076111.2 | Gene: | Rgl3 / 71746 | MGIID: | 1918996 | Length: | 709 | Species: | Mus musculus |
| Alignment Length: | 602 | Identity: | 123/602 - (20%) |
|---|---|---|---|
| Similarity: | 220/602 - (36%) | Gaps: | 190/602 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 463 LQEHGKD----VLVLERVAKQRGQHSAFKYTVMSGTP-------------------AKMLEHLLE 504
Fly 505 TRLGQSVGG---MDP-FLDDFLLTHIVFMPVVQLVDEL-----------ANYFHCDAHEDAQTPE 554
Fly 555 DREYIINFKKR---VIQFMQKWVMAVRHAA-FEEPSVCDFIEDLAAEVEADPDLNEETSIVHNVL 615
Fly 616 TQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTVIRPDDDIIFRVYCADHTYCTLRFPM 680
Fly 681 HTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSVKDHLDA 745
Fly 746 LTQLQEQECP-TEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELL---YHTFGRHHFGKITA 806
Fly 807 NLDVFLRRFNEVQYWIVTELVSTPSL--SKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMA 869
Fly 870 VSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFV-----------------GKLQPPLIP 917
Fly 918 FMPLLLKDMTFAHEGNKTSLDG-LVNFEK----MHMMAQTMRTIRFCRSRSLGLEPP------SP 971
Fly 972 KSEGEVRSYISSFRVID 988 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Epac | NP_001097202.2 | Crp | 28..>146 | CDD:223736 | |
| CAP_ED | 36..146 | CDD:237999 | |||
| DEP_Epac | 199..330 | CDD:239884 | |||
| CAP_ED | 352..463 | CDD:237999 | 123/602 (20%) | ||
| Crp | 373..525 | CDD:223736 | 20/88 (23%) | ||
| RasGEF_N | 489..594 | CDD:279012 | 29/142 (20%) | ||
| UBQ | 665..>714 | CDD:294102 | 9/48 (19%) | ||
| RasGEF | 766..1002 | CDD:214539 | 59/256 (23%) | ||
| Rgl3 | NP_076111.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..55 | 6/28 (21%) | |
| REM | 73..199 | CDD:100121 | 42/227 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 203..225 | 3/28 (11%) | |||
| RasGEF | 244..503 | CDD:214539 | 60/261 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 395..416 | 2/20 (10%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 502..604 | 123/602 (20%) | |||
| Interaction with HRAS, MRAS and RIT1. /evidence=ECO:0000269|PubMed:10869344, ECO:0000269|PubMed:11313946 | 611..706 | ||||
| RalGDS_RA | 612..697 | CDD:176351 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3629 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||