DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Epac and 4933421I07Rik

DIOPT Version :9

Sequence 1:	NP_001097202.2	Gene:	Epac / 35588	FlyBaseID:	FBgn0085421	Length:	1006	Species:	Drosophila melanogaster
Sequence 2:	NP_001357701.1	Gene:	4933421I07Rik / 71162	MGIID:	1918412	Length:	316	Species:	Mus musculus

Alignment Length:	248	Identity:	53/248 - (21%)
Similarity:	81/248 - (32%)	Gaps:	85/248 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   542 FHC------DAHEDAQTPEDREYIINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDLAAEVEA 600
            |.|      ..|:.|::    .::..|.:|:|:.:..    :|||:..||.||       .|.|.
Mouse     2 FRCFQTCRGSGHKKAKS----SWLGCFWRRLIRPLTH----LRHASRSEPKVC-------CENEQ 51

  Fly   601 DPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPP----NGQPICLFSGNATPSKTVIRPDDD 661
            :||          .::...|:.....:...|.....|    |...:||                |
Mouse    52 EPD----------SMSNHPRFDYKSREYIQQMIDYIPAAIQNRDHLCL----------------D 90

  Fly   662 IIFRVYCADHTYCT----LRFPMHTTAELIKACAADKLQ-----------LNRGPEDL------- 704
            |...:|   .||.|    |...|.|.|.....|..|:..           ..:.|:|.
Mouse    91 IFVAMY---RTYATTWEVLDLLMKTYASFRTDCIEDQQTKSAIFSFLFGWFQKFPQDFYESPDLA 152

  Fly   705 VLVEVKSNGERSV-FKDNDVSIPTGLSLNGRLFVSVKDHLDALTQLQEQECPT 756
            ||.:.......:| |.|.|......||:       .||. :|:|...|::|.|
Mouse   153 VLSQFTEYVRLNVPFGDGDTQAREPLSM-------FKDQ-EAITLRLEEDCAT 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Epac	NP_001097202.2	Crp	28..>146	CDD:223736
		CAP_ED	36..146	CDD:237999
		DEP_Epac	199..330	CDD:239884
		CAP_ED	352..463	CDD:237999
		Crp	373..525	CDD:223736
		RasGEF_N	489..594	CDD:279012	14/57 (25%)
		UBQ	665..>714	CDD:294102	14/70 (20%)
		RasGEF	766..1002	CDD:214539
4933421I07Rik	NP_001357701.1	REM	89..166	CDD:321967	17/95 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900