DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Epac and 1700001J03Rik

DIOPT Version :9

Sequence 1:	NP_001097202.2	Gene:	Epac / 35588	FlyBaseID:	FBgn0085421	Length:	1006	Species:	Drosophila melanogaster
Sequence 2:	XP_030110650.1	Gene:	1700001J03Rik / 69282	MGIID:	1916532	Length:	229	Species:	Mus musculus

Alignment Length:	168	Identity:	32/168 - (19%)
Similarity:	61/168 - (36%)	Gaps:	60/168 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   542 FHC------DAHEDAQTPEDREYIINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDLAAEVEA 600
            |.|      .:|:.|::    .:::.|.:|:|:.:..:    |||:..||.||       ::.|.
Mouse     2 FSCFQGSRGSSHKKAKS----GFLVRFWRRLIRPLSHF----RHASHSEPKVC-------SQNEQ 51

  Fly   601 DPD-LNEETSIVHN---VLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTVIRPDDD 661
            :|| :.......:|   .:.||..|             :|                 ..::.:|.
Mouse    52 EPDCMPRRPRFNYNSPEYVVQMIHY-------------IP-----------------AAVQHNDH 86

  Fly   662 IIFRVYCADH-----TYCTLRFPMHTTAELIKACAADK 694
            :..|::.|.:     |:..|...|.|.|.....|..|:
Mouse    87 VCIRIFLAMYPSYASTWKVLDLLMTTYASFRPDCVEDQ 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Epac	NP_001097202.2	Crp	28..>146	CDD:223736
		CAP_ED	36..146	CDD:237999
		DEP_Epac	199..330	CDD:239884
		CAP_ED	352..463	CDD:237999
		Crp	373..525	CDD:223736
		RasGEF_N	489..594	CDD:279012	14/57 (25%)
		UBQ	665..>714	CDD:294102	9/35 (26%)
		RasGEF	766..1002	CDD:214539
1700001J03Rik	XP_030110650.1	REM	89..183	CDD:100121	9/36 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900