Protein Alignment Epac and rasgrp2

DIOPT Version :10

• Sequence 1: NP_001097202.2
• Gene: Epac / 35588
• FlyBaseID: FBgn0085421
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_685135.5
• Gene: rasgrp2 / 557063
• ZFINID: ZDB-GENE-091118-124
• Length: 592
• Species: Danio rerio
• Alignment Length: 280
• Identity: 76/280 - (27%)
• Similarity: 118/280 - (42%)
• Gaps: 54/280 - (19%)

  Fly   709 VKSNGE--RSVFKDNDVSIPTGLSLNGRLFVSVK---------DHLDALTQLQEQECPTEGVDID 762
            ::.||:  ||:..|.| |||: .....:|..:|:         |||||.|
Zfish   104 LEQNGDVRRSLLIDID-SIPS-YEWRRQLDETVQKKRKTSLLFDHLDAST--------------- 151

  Fly   763 LEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELV 827
                    ||.|:|..|:..|..:...:  ||:|..|........|:.|:..||.|..||...::
Zfish   152 --------LAEHLTYMEYKSFCKILFQD--YHSFVMHGCTVDNPILERFITLFNSVSQWIQIMVL 206

  Fly   828 STPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFE 892
            |.|:..:|..::.:|||:|....:.||.|...|||.||||.:::||:.|...|.|..||:|....
Zfish   207 SKPTAQQRATVISEFIKVAERLLQLQNFNTLMAVVGGLSNSSIARLKNTQALISSDTRKVFDGLV 271

  Fly   893 ALIDPSRNHRAYRVFVGKLQPPLIPFMPLLLKDMTFAH-------EGNKTSLDGLVNFEKMHMMA 950
            .|:....|:..||....:......|.:.:.|||:...|       :..||.    ||..|.:.:.
Zfish   272 ELVTSFGNYSRYRQRFSECSGFRFPILGVHLKDLIAVHVALPDWIDPEKTR----VNLTKTYQLY 332

  Fly   951 QTMRTIRFCRSRSLGLEPPS 970
            ..:..:...:|     .||:
Zfish   333 AILEELALIQS-----TPPN 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Epac	NP_001097202.2	CAP_ED	36..146	CDD:237999
		DEP_Epac	199..330	CDD:239884
		CAP_ED	352..463	CDD:237999
		RasGEF_N	489..594	CDD:459873
		Ubl1_cv_Nsp3_N-like	652..>722	CDD:475130	5/14 (36%)
		RasGEF	766..1002	CDD:214539	59/212 (28%)
rasgrp2	XP_685135.5	None