Protein Alignment Epac and CG4853

DIOPT Version :10

• Sequence 1: NP_001097202.2
• Gene: Epac / 35588
• FlyBaseID: FBgn0085421
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_611222.2
• Gene: CG4853 / 36974
• FlyBaseID: FBgn0034230
• Length: 709
• Species: Drosophila melanogaster
• Alignment Length: 661
• Identity: 137/661 - (20%)
• Similarity: 243/661 - (36%)
• Gaps: 175/661 - (26%)

  Fly   431 TIVLKENNCH----------------LLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLERVAKQ 479
            |:..|||..|                |.|...|:..: .|....:|...|....|...::.:.:|
  Fly   114 TVETKENFNHQSHQKEIWHPVKQQSALARATPENALK-YRTTSNSTFASQATDSDERPVDPLGRQ 177

  Fly   480 RGQHSAFKYTVMSGTPA-----KMLEHLLETRLG---QSVGGMDPFLDDFLLTHIVFM--PVVQL 534
            ..| :....::||.:.|     :::..:..|.:|   .::...|...|.  |.|.|.|  |....
  Fly   178 LNQ-TFSNASLMSSSSAITGSDQVIGSVSSTTIGDKSSNISSCDSGHDG--LFHSVSMSAPWSHP 239

  Fly   535 VDELANYFHCDAHEDAQTPEDREYIINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDLAAEVE 599
            .|.|.:..:||....|. ..|...|:|                .|....||..|......|.::.
  Fly   240 RDTLTDSLYCDIPSSAD-ESDAVSILN----------------THLKITEPFDCQTAPVYAKDIP 287

  Fly   600 ADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFS-GNATPSKTVIRPD--DD 661
            ...:|:...:::.|..|:..|:.......               ||| .:...||.:.:.|  ::
  Fly   288 KKGNLDSVVNLLINNNTKDLRFAFLTTSR---------------LFSPPHQLLSKIIAKIDNEEE 337

  Fly   662 IIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSV-----FKDN 721
            .:.|:                ..|.:..|..|      ...:|:|.|:::  :|:|     |.|
  Fly   338 NVLRL----------------LNEWLDTCPGD------FSHELLLQELEN--KRNVKGLAAFLD- 377

  Fly   722 DVSIPTGLSL---NGRLFVSVKDHLDALTQLQEQECPTEGVDIDLEILSTK-------------- 769
              .||..|:.   |||         ..|..|..::.....:.....|.|.|
  Fly   378 --GIPQALAQKDENGR---------SQLNNLLTKQSSASSLGRQSSIKSLKRFAANVYKTDNVLN 431

  Fly   770 ------ELAYHITLFEW--------DLFWAVHEYELLYHTFGRHHFGKITAN------LDVFLRR 814
                  |||:.:...|:        :.|..:.|.:.|.....:...|.:.:|      :|.:::.
  Fly   432 NCSSAFELAHQLYAIEYAYLSQIRLEEFVEILEKDELKTCISQTKAGTLGSNCISQVTIDSYVQW 496

  Fly   815 FNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEK 879
            ||::.|...||::.....|:|..::..:::.|..|....|.|:..|::..|:..|::||::||.|
  Fly   497 FNQLSYLTATEILKLGKKSQRAQMIDFWVETALECFNTGNFNSLMAILTALNLTAIARLKKTWAK 561

  Fly   880 IPSKFRKIFQEFEALIDPSRNH------------RAYRVFVGKLQPPLIPFMPLLLKDMTFAHEG 932
            :.:   ..|:..|..:|||.|.            |:.|....:::..:|||..|.|||:...:|.
  Fly   562 VQT---TKFEGLEHQMDPSSNFLNYRSTMKAAVWRSEREMANEIERAIIPFFSLFLKDLHAINES 623

  Fly   933 NKTSL-DGLVNFEK-MHMMAQTMRTIRFCRSRSLG----LEPPSPKSEGEVRSYISSFRVIDNQR 991
            ::|.| :|.:|||| :|:..|.         |:.|    |:.|..:....| ||:....|:....
  Fly   624 HETKLANGYINFEKCLHLGTQL---------RNFGKWQRLDCPYEQLPSVV-SYLLKAEVLSEDL 678

  Fly   992 VLTAMSQKVEP 1002
            ::.| |.:.||
  Fly   679 LMKA-SYESEP 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Epac	NP_001097202.2	CAP_ED	36..146	CDD:237999
		DEP_Epac	199..330	CDD:239884
		CAP_ED	352..463	CDD:237999	10/47 (21%)
		RasGEF_N	489..594	CDD:459873	24/114 (21%)
		Ubl1_cv_Nsp3_N-like	652..>722	CDD:475130	14/76 (18%)
		RasGEF	766..1002	CDD:214539	66/287 (23%)
CG4853	NP_611222.2	REM	292..>365	CDD:470601	17/109 (16%)
		RasGEF	438..638	CDD:459872	51/202 (25%)