DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Epac and 4930596D02Rik

DIOPT Version :9

Sequence 1:	NP_001097202.2	Gene:	Epac / 35588	FlyBaseID:	FBgn0085421	Length:	1006	Species:	Drosophila melanogaster
Sequence 2:	NP_001028938.1	Gene:	4930596D02Rik / 239036	MGIID:	3588288	Length:	216	Species:	Mus musculus

Alignment Length:	145	Identity:	36/145 - (24%)
Similarity:	62/145 - (42%)	Gaps:	26/145 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   490 VMSGTPAKMLEHLLETRLGQSVGGMDP-FLDDFLLTHIVFMPVVQLVDEL---ANYFHCDAHEDA 550
            |.:.|..|::.||:     .|:...|| |:..||.|:..|...:|:::.|   ..||..::.||.
Mouse    69 VSADTLKKLVNHLV-----PSLQSGDPFFIPAFLSTYRRFATTLQVLNLLFKRYEYFRPNSEEDE 128

  Fly   551 QTPEDREYIINFKKRVIQFMQKWVMAVRHAAFEEPS---VCDFIEDLAAEVEADPDLNEETSIVH 612
            |.          |..:..|:..| |......|.:.|   ..::::...:....|.|||..   |.
Mouse   129 QV----------KNTLCSFLNTW-MDKNTEDFCQTSDLLPLNYLKTYLSMNMPDSDLNVR---VT 179

  Fly   613 NVLTQMARYQEDRNQ 627
            .:|||:.:.|.:.:|
Mouse   180 RLLTQLQKEQANVSQ 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Epac	NP_001097202.2	Crp	28..>146	CDD:223736
		CAP_ED	36..146	CDD:237999
		DEP_Epac	199..330	CDD:239884
		CAP_ED	352..463	CDD:237999
		Crp	373..525	CDD:223736	11/35 (31%)
		RasGEF_N	489..594	CDD:279012	26/110 (24%)
		UBQ	665..>714	CDD:294102
		RasGEF	766..1002	CDD:214539
4930596D02Rik	NP_001028938.1	REM	73..188	CDD:100121	33/133 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900