Protein Alignment Cyp6a2 and DIT2

DIOPT Version :10

• Sequence 1: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 473
• Identity: 94/473 - (19%)
• Similarity: 168/473 - (35%)
• Gaps: 111/473 - (23%)

  Fly    69 PFVGFYFLHKPAAFIVD-TQLAK---------------------NILI----------KDFSNFA 101
            |.:.||.:..|..|.:| |:|..                     |||:          ||...||
Yeast    34 PTIPFYVVFLPVIFPIDQTELYDLYIRESMEKYGAVKFFFGSRWNILVSRSEYLAQIFKDEDTFA 98

  Fly   102 DRGQFHNGRDDPLT-------QHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKV 159
            ..|   |.:..|.:       .::.:..|..|::.|..:    |:|...|....:.|.::....:
Yeast    99 KSG---NQKKIPYSALAAYTGDNVISAYGAVWRNYRNAV----TNGLQHFDDAPIFKNAKILCTL 156

  Fly   160 ITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLT 224
            |..::...|..  :.:..|..|...|.|...|.|.:...|....:.|.....::...:.|...||
Yeast   157 IKNRLLEGQTS--IPMGPLSQRMALDNISQVALGFDFGALTHEKNAFHEHLIRIKKQIFHPFFLT 219

  Fly   225 MFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALR---ERENFKRNDFMNLLIELKQKGRVTL 286
            ........:.||.:.........:..::.|.|.:...   |:..|..:|.            :..
Yeast   220 FPFLDVLPIPSRKKAFKDVVSFRELLVKRVQDELVNNYKFEQTTFAASDL------------IRA 272

  Fly   287 DNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQ-NQDIQDRLRNEIQTVLEEQEGQ 350
            .|.|:|   |..:|...:.:..|||.|......:..||.||: :.:.|::||.|:..:.:.
Yeast   273 HNNEII---DYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDP---- 330

  Fly   351 LTYESIKAMTYLNQVISETLRLY----TLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAY- 410
               :.:..:..||..:.|.:|:|    |::.....|..         ||    |.:::||...|
Yeast   331 ---KGLADLPLLNAFLFEVVRMYPPLSTIINRCTTKTC---------KL----GAEIVIPKGVYV 379

  Fly   411 --------HRDEDLYPNPETFDPERFSPEKVAARESVEW---------LPFGDGPRNCIGMRFGQ 458
                    |..:......:.|.|||:..:....|::  |         ..|..|.|.|:|.:...
Yeast   380 GYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKN--WRMAKNRCAVTGFHGGRRACLGEKLAL 442

  Fly   459 MQARIGLAQIISRFRVSV 476
            .:.||.||:::.:||.|:
Yeast   443 TEMRISLAEMLKQFRWSL 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	94/473 (20%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	86/442 (19%)