DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a2 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_523628.1	Gene:	Cyp6a2 / 35587	FlyBaseID:	FBgn0000473	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	111/484 - (22%)
Similarity:	210/484 - (43%)	Gaps:	76/484 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 FFYDYYNKYRKSGFPFVGFYFL-HKPAAFIV--DTQLAKNILIKDFSNFADRGQFHNGRDDPLTQ 116
            ||...|..:...|    |.:.| ..|.:|::  |..:||:|| ||.:....:|......|..:.:
plant   128 FFIPLYELFLTYG----GIFRLTFGPKSFLIVSDPSIAKHIL-KDNAKAYSKGILAEILDFVMGK 187

  Fly   117 HLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMAR 181
            .|...||:.|:..|:.:.|..   ..|::...:....|...::..:...||..|..:|::.|.:|
plant   188 GLIPADGEIWRRRRRAIVPAL---HQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSR 249

  Fly   182 FTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGK---LLTMFVFSFP----------KL 233
            .|.|:||...|..:.::|.....    :.:.|:|.:|..:   :..:.|:..|          |:
plant   250 LTLDIIGKAVFNYDFDSLTNDTG----VIEAVYTVLREAEDRSVSPIPVWDIPIWKDISPRQRKV 310

  Fly   234 ASRLRMRMMPEDVHQFFMRLVNDTI---------ALRERENFKRNDFMN-----LLIELKQKGRV 284
            |:.|              :|:|||:         .:.|.|.....::||     :|..|...|
plant   311 ATSL--------------KLINDTLDDLIATCKRMVEEEELQFHEEYMNERDPSILHFLLASG-- 359

  Fly   285 TLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEG 349
                    :.:...:|...:....:||.|||::.:::..|.|.....:..:|:.|:.:|:.::..
plant   360 --------DDVSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGDRFP 416

  Fly   350 QLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDE 414
              |.:.:|.:.|..:|::|:||||...|.|.|:::::.::..:.   |::|..:.|.....||..
plant   417 --TIQDMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDILGEYP---IKRGEDIFISVWNLHRSP 476

  Fly   415 DLYPNPETFDPERF---SPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
            ..:.:.|.|:|||:   .|......::..:||||.|||.|||..|...:..:.:|.:|.||...:
plant   477 LHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQI 541

  Fly   477 CDTTEIPLKYSPMSIVLGTVGGIYLRVER 505
            ..... |:|.: ....:.|..|:.|.|.:
plant   542 APGAP-PVKMT-TGATIHTTEGLKLTVTK 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	109/479 (23%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	111/484 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810