DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a2 and LUT1

DIOPT Version :9

Sequence 1:	NP_523628.1	Gene:	Cyp6a2 / 35587	FlyBaseID:	FBgn0000473	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	111/466 - (23%)
Similarity:	209/466 - (44%)	Gaps:	84/466 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 PAAFIV--DTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFN-----LDGKKWKDMRQRLTPT 136
            |..|::  |..:||::| :::..:|      .|....:::.||.     .:|..|...|:.:.|:
plant   118 PRNFVIVSDPAIAKHVL-RNYPKYA------KGLVAEVSEFLFGSGFAIAEGPLWTARRRAVVPS 175

  Fly   137 FTSGKMKFMFPTVIKVSEEFVKVITEQV-------------PAAQNGAVLEIKELMARFTTDVIG 188
                           :...::.||.|:|             |.|::|:.:.::...::.|.||||
plant   176 ---------------LHRRYLSVIVERVFCKCAERLVEKLQPYAEDGSAVNMEAKFSQMTLDVIG 225

  Fly   189 TCAFGIECNTLRT--PVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRM---RMMPEDVHQ 248
            ...|....::|.|  ||.      :.|:|.::..:|.:..:..:.|:.:..::   ::..|....
plant   226 LSLFNYNFDSLTTDSPVI------EAVYTALKEAELRSTDLLPYWKIDALCKIVPRQVKAEKAVT 284

  Fly   249 FFMRLVNDTIA----LRERENFKRND--FMN-----LLIELKQKGRVTLDNGEVIEGMDIGELAA 302
            .....|.|.||    :.|||..:.||  ::|     :|       |..|.:.|.:..:   :|..
plant   285 LIRETVEDLIAKCKEIVEREGERINDEEYVNDADPSIL-------RFLLASREEVSSV---QLRD 339

  Fly   303 QVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVIS 367
            .:....|||.||:.|.:::.||.|::|.....:.:.|:..|||.:..  .:|.||.:.|:.:.|:
plant   340 DLLSMLVAGHETTGSVLTWTLYLLSKNSSALRKAQEEVDRVLEGRNP--AFEDIKELKYITRCIN 402

  Fly   368 ETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEK 432
            |::|||...|.|.|:|....::||:.|  :..|..::|.....||..:::...|.|.||||..:.
plant   403 ESMRLYPHPPVLIRRAQVPDILPGNYK--VNTGQDIMISVYNIHRSSEVWEKAEEFLPERFDIDG 465

  Fly   433 VAARES---VEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLG 494
            ....|:   .:::||..|||.|:|.:|..|:|.:.||..:.|..|.:.....|.:   .....:.
plant   466 AIPNETNTDFKFIPFSGGPRKCVGDQFALMEAIVALAVFLQRLNVELVPDQTISM---TTGATIH 527

  Fly   495 TVGGIYLRVER 505
            |..|:|::|.:
plant   528 TTNGLYMKVSQ 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	110/461 (24%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	111/466 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810