DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a2 and CYP705A32

DIOPT Version :9

Sequence 1:	NP_523628.1	Gene:	Cyp6a2 / 35587	FlyBaseID:	FBgn0000473	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_188731.1	Gene:	CYP705A32 / 821645	AraportID:	AT3G20950	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	118/515 - (22%)
Similarity:	203/515 - (39%)	Gaps:	110/515 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IYLLIAISSLLAY-LYHRNFNYWNRRGVPHDA-------PHP-------LYGNMVGFRKNRVMHD 54
            |::|..:.||:.| |:.|.         |.|:       |.|       ...|.:....:.::|.
plant    14 IFILFCLFSLICYSLFFRK---------PKDSRAGRDLPPSPPSFPVGSPQSNNLHLLLSALVHK 69

  Fly    55 FFYDYYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPL----T 115
            .|.....||.    |.:.....|.|........:|..|......|.:.||  |....:.|    :
plant    70 SFQKISYKYG----PLLHLRVFHVPIVLASSASVAYEIFKAQDVNVSSRG--HAPAGESLLFGSS 128

  Fly   116 QHLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVS-----EEFVKVITEQVPAAQNGAVLEI 175
            ...|...|..:|.||:.:.       .|.:.|..::.|     :|..:.....:..|.....::|
plant   129 SFFFAPYGDYFKFMRKLIA-------TKLLGPQALERSRKIRADELDRFYRNLLDKAMKKESVDI 186

  Fly   176 KELMARFTTDVIGTCAFGIECN-------TLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKL 233
            .|..|:...::|.....|..|:       .:|..|.:...:.:::|..|           .|.|.
plant   187 VEEAAKLNNNIICKMIMGRSCSEDNGEAERVRGLVIESTALTKQIFLGM-----------IFDKP 240

  Fly   234 ASRLRMRMMPEDVHQF--FMRLVNDTIALRER---ENFKRNDFMNLLIEL----KQKGRVTLDNG 289
            ..:|.:.:..:|:...  |..|:...:...|.   :::|.||.|:||:|.    ..:.::|.::
plant   241 LKKLGISLFQKDIKSVSRFDELLEKILVEHEERMGKHYKANDMMDLLLEAYGDENAEYKITRNH- 304

  Fly   290 EVIEGMDIGELAAQVFV-FYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTY 353
                       ...:|| ..:||.:||:.|:.:.:.||..|.:|.:|||.||::|:...  :|..
plant   305 -----------IKSLFVDLVIAGTDTSAQTIEWTMAELINNPNILERLREEIESVVGNT--RLVQ 356

  Fly   354 ES-IKAMTYLNQVISETLRLYT-----LVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHR 412
            |: :..:.||..|:.|.|||:.     |....||..|..:.:|       || |.:::...|..|
plant   357 ETDLPNLPYLQAVVKEGLRLHPPGAVFLRTFQERCELKGFYIP-------EK-TLLVVNVYAIMR 413

  Fly   413 DEDLYPNPETFDPERF-----SPEKVAARESV-EWLPFGDGPRNCIGMRFGQMQARIGLA 466
            |..|:.:||.|.||||     |.::...||.| :::||..|.|.|.|.....:.  :|.|
plant   414 DPKLWEDPEEFKPERFIASSRSGQEDEIREEVLKYMPFSTGRRGCPGSNLAYVS--VGTA 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	109/476 (23%)
CYP705A32	NP_188731.1	p450	16..514	CDD:299894	117/513 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920